Titlebook: Research in Computational Molecular Biology; 16th Annual Internat Benny Chor Conference proceedings 2012 Springer-Verlag Berlin Heidelberg

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,LoopWeaver – Loop Modeling by the Weighted Scaling of Verified Proteins,niques have the advantage of producing a higher proportion of predictions with sub-angstrom accuracy, when compared with . techniques, but the disadvantage of also producing a higher proportion of clashing or highly inaccurate predictions. We introduce LoopWeaver, a database method that uses multidi

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A Robust Method for Transcript Quantification with RNA-seq Data,the abundance of transcript isoforms. Accurate abundance estimation or . of isoforms is critical for downstream differential analysis (e.g. healthy vs. diseased cells), but remains a challenging problem for several reasons. First, while various types of algorithms have been developed for abundance e

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TrueSight: Self-training Algorithm for Splice Junction Detection Using RNA-seq,limited read length of NGS data, it is extremely challenging to accurately map RNA-seq reads to splice junctions, which is critically important for the analysis of alternative splicing and isoform construction. Several tools have been developed to find splice junctions by RNA-seq ., without the aid

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Synthetic Sequence Design for Signal Location Search,igns employing combinatorial group testing and balanced Gray codes. Experiments in polio and adenovirus demonstrate the efficiency and generality of this procedure. In this paper, we give a new class of consecutive positive group testing designs, which offer a better tradeoff of cost, resolution, an

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