Titlebook: Research in Computational Molecular Biology; 24th Annual Internat Russell Schwartz Conference proceedings 2020 Springer Nature Switzerland

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: Fast and Optimal Sequence-to-Graph Alignmentt alignment graph. To find a shortest path, we instantiate the A. paradigm with a novel domain-specific heuristic function that accounts for the upcoming subsequence in the query to be aligned, resulting in a provably optimal alignment algorithm called ...Experimental evaluation of . shows that it i

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Stochastic Sampling of Structural Contexts Improves the Scalability and Accuracy of RNA 3D Module Idconnected by loops whose local conformations are critical determinants of global 3D architectures. Such local 3D structures consist of conserved sets of non-canonical base pairs, called RNA modules. Their prediction from sequence data is thus a milestone toward 3D structure modelling. Unfortunately,

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Lower Density Selection Schemes via Small Universal Hitting Sets with Short Remaining Path Lengthhere is a tight relationship between universal hitting sets and minimizers schemes, where minimizers schemes with low density (i.e., efficient schemes) correspond to universal hitting sets of small size. Local schemes are a generalization of minimizers schemes which can be used as replacement for mi

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978-3-030-45256-8Springer Nature Switzerland AG 2020

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Research in Computational Molecular Biology978-3-030-45257-5Series ISSN 0302-9743 Series E-ISSN 1611-3349