Titlebook: Research Ethics in Epidemics and Pandemics: A Casebook; Susan Bull,Michael Parker,Jantina de Vries Book‘‘‘‘‘‘‘‘ 2024 PAHO and Editors 2024

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Introduction: Research Ethics and Health Policy in Epidemics and Pandemics,novel research to inform real-time decision-making and pandemic responses. While research is vitally important, however, emergencies are radically non-ideal contexts for its conduct, due to exceptional uncertainty, urgency, disruption, health needs, and strain on existing health systems, amongst oth

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Setting Research Priorities,and emergencies, given the increased need for relevant research findings to address health needs, and the multiple adverse ways that emergencies can impact capacities to conduct research. At international, national and local levels, careful consideration is needed of which research topics should be

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Boundaries Between Research, Surveillance and Monitored Emergency Use,o research, non-research activities, such as prevention and control interventions, and surveillance, are conducted. The boundaries between research and non-research responses can rapidly blur during a public health emergency such as the COVID-19 pandemic. There may be common elements between these t

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Ethics Review Challenges,andards. The Ebola and Zika outbreaks highlighted the importance of devising agile processes for ethics review in emergencies, and international research ethics guidelines stress the duty to depart from standard processes for ethics review in emergency circumstances. However, before the COVID-19 pan

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Ethical Issues Associated with Managing and Sharing Individual-Level Health Data,data, bringing into sharp focus the importance of thinking about what constitutes ethical use of data in a public health emergency. The timely and appropriate use of such data (e.g. data from public health surveillance, electronic health records and research projects) has great potential to contribu

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Dimensions of Vulnerability,ated, even when the infectious agent is nonselective, people and contexts are affected differently. Frequently these differences are not due to individual characteristics but to precarious contexts that became even less safe during emergencies, and exacerbate inequalities. An unknown disease that af