书目名称 | Replicating Vaccines | 副标题 | A New Generation | 编辑 | Philip R. Dormitzer,Christian W. Mandl,Rino Rappuo | 视频video | | 概述 | Highlights new approaches to the generation of live vaccines.Includes discussion of risks and safety aspects.Covers a variety of infectious organisms.Includes supplementary material: | 丛书名称 | Birkhäuser Advances in Infectious Diseases | 图书封面 |  | 描述 | Technological advances, together with a better understanding of the molecular biology of infectious microorganisms, are creating exciting possibilities for a new generation of replicating vaccines.Historically, live vaccines have been either directly derived from a natural source or attenuated by empirical approaches using serial passages and host cell adaptation.Currently, we are witnessing a quantum leap in our technological capabilities to specifically modify the genetic make-up of viruses and bacteria, making it possible to generate improved live vaccines and to develop completely new types of replicating vaccines, such as vectored vaccines, single-round infectious vaccines and replicon vaccines.This book highlights some of the most exciting recent developments towards a new generation of replicating vaccines. | 出版日期 | Book 2011 | 关键词 | vaccines | 版次 | 1 | doi | https://doi.org/10.1007/978-3-0346-0277-8 | isbn_softcover | 978-3-0348-0316-8 | isbn_ebook | 978-3-0346-0277-8Series ISSN 2504-3811 Series E-ISSN 2504-3838 | issn_series | 2504-3811 | copyright | Springer Basel AG 2011 |
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