Titlebook: Renal Cell Carcinoma; Molecular Biology, I Ronald M. Bukowski (Director),Andrew C. Novick (Ch Book 20001st edition Springer Science+Busines

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Renal Cell Carcinomatage, largely caused by more frequent and liberal use of modern radiological imaging techniques. Nonetheless, this tumor is still commonly diagnosed late because it is characterized by few symptoms and signs directly related to the renal primary site. It has been called the “internist’s tumor” becau

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Offstage

Book 20001st editionnetic abnormalites associated with the development of renal cancer were first described. Abnormalities of the VHL gene have also been detected in sporadic clear cell carcinoma, and it has now been recognized that approximately 80 % of these tumors will demonstrate ch- acteristic alterations. Current

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2364-1134 nocarcinoma. The annual incidence of this tumor appears to be rising and approximately 12,000 individuals die from this cancer annually in the United States. One third of patients who present have metastatic disease at the time of diagnosis, and another 40% who undergo nephrectomy will ultimately de

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SPALL

Prognostic Factors in Metastatic Renal Cell Carcinoma estimated 5-yr survival of 0–20% .. Unfortunately, approximately one-third of patients has metastatic disease on initial presentation ., and therefore, effective treatment strategies for this disease are clearly needed.

FLIP

Laparoscopic Surgery for Renal Cell Carcinomally. Herein, we present the Cleveland Clinic experience with laparoscopic renal surgery for RCC. For the purposes of this chapter, laparoscopic techniques for renal cell cancer will be limited to two primary categories: (1) laparoscopic radical nephrectomy, and (2) laparoscopic renal cryoablation.

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The Pathology of Renal Neoplasmssis, more modern concepts of subtyping renal cell carcinoma have evolved based on histogenesis. Renal cell carcinomas are currently classified as representing clear cell, papillary (chromophil), chromophobe, collecting duct, and unclassified types, which include the pure sarcomatoid variant (.).

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Screening for Renal Cell Carcinomate cancer, it is clear that early detection in the case of renal cell carcinoma (RCC) would be beneficial. In this chapter, we will assess the rationale for screening for RCC, examine the diagnostic tests available for screening, and review screening recommendations for target populations, including the recently described familial forms of RCC.