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Titlebook: Renal Cell Carcinoma; Molecular Features a Mototsugu Oya Book 2017 Springer Japan KK 2017 Molecular-targeted therapy.TKI.anti-angiogenic ag

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Mammalian Targets of Rapamycin Inhibitors: Temsirolimus and Everolimus,ism; the mTOR pathway appears to be deregulated in a number of human malignancies including renal cell carcinoma..To date, two mTOR inhibitors have been registered for the treatment of renal cell carcinoma: temsirolimus (for treatment-naïve patients with poor prognostic features) and everolimus (for
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Forthcoming Drugs for Metastatic Renal Cell Carcinoma Therapy,t of advanced renal cell carcinoma (RCC). However, in most cases, RCC cells eventually develop drug resistance or drug treatments are stopped because of their adverse events (AEs)..TKIs that are selective for targeted molecules have potent antitumor effects and produce few side effects are ideal. Al
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