Titlebook: Relaxin and the Fine Structure of Proteins; Christian Schwabe,Erika E. Büllesbach Book 1998 Springer-Verlag Berlin Heidelberg 1998 Protein

为宠爱

membrane

杠杆

可行

GILD

Comedienne

The N-Terminal Region of the Relaxin A Chain, N-terminal region of the A chain lends itself to modifications or even to total exchange. The questions to be answered then were: 1) is the A chain N-terminal region important, and if so, 2) what is its role?

忘川河

The Receptor-Binding Site of Relaxin,ive charge is required. Another important question pertains to the distance between the core of relaxin and the guanidino group which could be answered by incorporation of homoarginine at the binding-site.

同谋

The Relaxin Receptor,ction methods quite difficult. In contrast, insulin has low nonspecific binding, but shows specific binding up to 80% of the total radioactivity bound. The relaxin system gives 50% specific binding at best and usually shows around 30%, and that only after major efforts in tracer design, preparation and purification.

诙谐

intoxicate

The Initial Approach to Receptor-Binding Site Studies,Clearly the receptor-interaction site is the most interesting feature of a hormone, but how would one start to look for it? We knew that at the same time several other research groups were having this discussion, among them one of the most successful biotechnology companies, and that gave our efforts a certain sense of urgency.