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Titlebook: Regulatory Peptides and Cognate Receptors; Dietmar Richter Book 1999 Springer-Verlag Berlin Heidelberg 1999 Alanin.G Proteine.G Proteins.N

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发表于 2025-3-21 18:15:18 | 显示全部楼层 |阅读模式
书目名称Regulatory Peptides and Cognate Receptors
编辑Dietmar Richter
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概述This book summarizes the latest advances in the important and fast-moving field of regulatory peptides and receptors.Includes supplementary material:
丛书名称Results and Problems in Cell Differentiation
图书封面Titlebook: Regulatory Peptides and Cognate Receptors;  Dietmar Richter Book 1999 Springer-Verlag Berlin Heidelberg 1999 Alanin.G Proteine.G Proteins.N
描述In the last two decades, our knowledge on regulatory peptides and their cognate receptors, most of which are members of the seven transmembrane receptor families, has increased enormously. Regulatory peptides are small proteins which, besides their hormonal functions in regulating cellular metabolism in various tissues, may also act as neurotransmitters, and thus they often carry the prefix "neuro". Many of the cognate receptors involved in transducing the peptidergic signal across the cell membrane via a familiy of G proteins exist in multiple forms, the number of which frequently exceeds that of the corresponding peptide ligands. In this book, various peptide-receptor systems are discussed, e.g CRF, somatostatin, TRH, opioid peptides, vasopressin, and oxytocin. It also discusses new strategies such as "reverse physiology" to uncover new peptides and orphan receptors.
出版日期Book 1999
关键词Alanin; G Proteine; G Proteins; Nervous System; Neuropeptide; Receptors; Rezeptoren; Signal Transduction; Si
版次1
doihttps://doi.org/10.1007/978-3-540-49421-8
isbn_softcover978-3-662-12908-1
isbn_ebook978-3-540-49421-8Series ISSN 0080-1844 Series E-ISSN 1861-0412
issn_series 0080-1844
copyrightSpringer-Verlag Berlin Heidelberg 1999
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978-3-662-12908-1Springer-Verlag Berlin Heidelberg 1999
发表于 2025-3-22 07:52:11 | 显示全部楼层
Regulatory Peptides and Cognate Receptors978-3-540-49421-8Series ISSN 0080-1844 Series E-ISSN 1861-0412
发表于 2025-3-22 11:34:21 | 显示全部楼层
Dietmar RichterThis book summarizes the latest advances in the important and fast-moving field of regulatory peptides and receptors.Includes supplementary material:
发表于 2025-3-22 15:52:22 | 显示全部楼层
,The ‘Chicken and Egg’ Problem of Co-evolution of Peptides and Their Cognate Receptors: Which Came Frowth factor, which have a single membrane-spanning domain and an intracellular ligand-activated tyrosine kinase domain (see McInnes and Sykes 1997), that for the peptide Phe-Met-Arg-Phe-amide which contains an integral ligand-gated sodium channel (Lingueglia et al. 1995), and the 200-kDa head-activ
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CRF and CRF Receptors,) and cognitive disease (reviewed by De Souza 1995). The characterization of the primary structure of CRF (Spiess et al. 1981) purified on the basis of its hypophysiotropic activity (Vale et al. 1981) enabled rapid progress in the understanding of the physiology, biochemistry and anatomy of CRF in t
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The Oxytocin Receptor,ies using such peptides did allow a degree of speculation on structural aspects of the receptor-ligand binding interaction, though only upon the cloning of the receptor some 40 years after the elaboration of the peptide hormone has it been possible to pursue such studies in detail.
发表于 2025-3-23 08:55:04 | 显示全部楼层
Targeted Mutagenesis of the Murine Opioid System,iologically relevant paradigms. Genetically modified mice, mostly those harboring a null allele for an opioid gene, behave consistently with several hypotheses based on earlier pharmacological data, but unexpected results have been observed as well. We review here what those experiments have found a
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