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Titlebook: Regulatory Mechanisms of Neuron to Vessel Communication in the Brain; Fiorenzo Battaini,Stefano Govoni,Marco Trabucchi Conference proceedi

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Structural and Functional Polarity of The Blood-Brain Barrier,pounds to pass. Over the past two decades, our understanding of blood-brain barrier function has been advanced by recognition of the importance of carrier-mediated transport processes which facilitate the permeation of selected polar compounds across this lipid barrier. In most cases, however, kinet
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Active and Facilitated Amino Acid Transport Mechanisms Across the Brain Capillary Endothelial Cellsamino acids through the blood-brain barrier. The isolation procedures available as well as the motphological aspects and the enzyme activities of isolated brain microvessels are also described. This . equivalent of the blood-brain barrier has been used to study the kinetic characteristics and the po
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Central Noradrenergic Innervation of Cerebral Microvessels: Implications for an Autonomic Nervous Sr function. As research focuses on determining the exact anatomical site of this regulation (muscle layer, endothelial cells or even glial cells) and the precise mechanism of action (opening of tight junctions, pinocytosis, membrane permeability, etc.), it is important not to loose sight of the over
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Innervation of the cerebral vasculature and its putative role in the coupling of flow to metabolismto account for the phenomenon: Increased neuronal metabolic activity will give rise to the accumulation of vasoactive catabolites, which decrease vascular resistance and thereby increase blood flow until normal homeostasis is reestablished. However, the hypothesis does not account for the disproport
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Peptidergic Innervation of the Cerebral Vasculature and its Functional Signfiicance,tely 20. However, the dominant factors primarily responsible for the dynamic regulation of cerebral blood flow have long been considered to be vasoactive products of cellular metabolism, with perivascular hydrogen ions, potassium ions and adenosine being the most favoured candidates. Many cerebrovas
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Physiological and Pathological Events Mediated by Capillary Neurotransmitter Receptors, transport processes operating in the cerebral endothelial cells is of great current interest. From biochemical and electron microscopic studies it became evident that, contrary to the classical view, histamine is a potent activator of the pinocytosis and the albumin transport in the cerebral endoth
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Dynamic Variations of the Extracellular Space in the Central Nervous System,large changes in the concentration of extracellular ion occur. Such changes are accompanied by changes in the extracellular space (ES) size, which can shrink by up to 60%. The changes in ES size can be rapid, localized and also rapidly reversible. Several mechanisms can account for the ES changes: K
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