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Titlebook: Regulatory Mechanisms in Breast Cancer; Advances in Cellular Marc E. Lippman,Robert B. Dickson Book 1991 Kluwer Academic Publishers 1991 bi

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Antiestrogen therapy for breast cancer: Current strategies and potential causes for therapeutic failng in breast tumors. Several compounds were evaluated, but only tamoxifen was developed further because of the low incidence of side effects and the demonstrated efficacy in phase II/III clinical trials [12, 13].
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Estrogen and progesterone receptorstrogen in the growth of breast cancer are the marked decrease in tumor growth following ovariec- tomy and remission following treatment with antiestrogens and progestins [7]. Consequently, the estrogen receptor (ER) is used to predict those patients who benefit from hormonal therapy.
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Steroids, growth factors, and cell cycle controls in breast canceramental role for estrogen in breast cancer progression and growth. Furthermore, the fact that treatment with compounds that act via antagonism of estrogen action, i.e., synthetic antiestrogens and perhaps progestins, leads to remission in a high proportion of patients with receptor-positive tumors adds additional weight to this view [6–8].
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understanding at the nexus between the forest sector on the one hand and strategic management on the other, has led to failures in many countries to realise the potential that forest sector development offers. This important new book adopts a more holistic approach to propose a new theoretical fram
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