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Titlebook: Regulatory Mechanisms in Breast Cancer; Advances in Cellular Marc E. Lippman,Robert B. Dickson Book 1991 Kluwer Academic Publishers 1991 bi

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书目名称Regulatory Mechanisms in Breast Cancer
副标题Advances in Cellular
编辑Marc E. Lippman,Robert B. Dickson
视频video
丛书名称Cancer Treatment and Research
图书封面Titlebook: Regulatory Mechanisms in Breast Cancer; Advances in Cellular Marc E. Lippman,Robert B. Dickson Book 1991 Kluwer Academic Publishers 1991 bi
描述In Breast Cancer: Cellular and Molecular Biology [Kluwer Academic Pub­ lishers, 1988], we tried to present an introduction to the emerging basic studies on steroid receptors, oncogenes, and growth factors in the regulation of normal and malignant mammary epithelium. The response to this volume was superb, indicating a tremendous interest in basic growth regulatory mechanisms governing breast cancer and controlling its malignant progres­ sion. In the two years since its publication, much new and exciting in­ formation has been published and the full interplay of regulatory mechanisms is now beginning to emerge. We have divided this book into four sections that we hope will unify important concepts and help to crystallize areas of consensus and/or disagreement among a diverse group of basic and clinical scientists working on the disease. The first section is devoted to studies on oncogenes, antioncogenes, proliferation, and tumor prognosis. The first chapter, by Sunderland and McGuire, introduces the characteristics of breast cancer as studied by patho­ logists to establish prognostic outcome. Of particular interest is a new proto­ oncogene called HER-2 (or neu), which is rapidly bec
出版日期Book 1991
关键词biology; carcinogenesis; carcinoma; cell; development; gene expression; metastasis; molecular biology; oncog
版次1
doihttps://doi.org/10.1007/978-1-4615-3940-7
isbn_softcover978-1-4613-6758-1
isbn_ebook978-1-4615-3940-7Series ISSN 0927-3042 Series E-ISSN 2509-8497
issn_series 0927-3042
copyrightKluwer Academic Publishers 1991
The information of publication is updating

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Local effects of growth factorsRegulation of mammary gland growth and morphogenesis provides a striking example of the interplay of systemic ’classical’ hormones with more recently discovered growth factors. Both are probably required for mammary morphogenesis and functional differentiation; an understanding of both is critical to understanding the problem of mammary cancer.
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Cell proliferation in metazoans: Negative control mechanismsTwo methods of attack are used most frequently against a new theory: the first one is to claim that the new theory is wrong; the second one is to claim that it is not new.
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