Titlebook: Regulation of Hepatic Metabolism; Intra- and Intercell Ronald G. Thurman,Frederick C. Kauffman,Kurt Junge Book 1986 Plenum Press, New York

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Separation of Functionally Different Liver Cell Typeslic dynamics. Regulation of synthetic and catabolic pathways and functional coordination among the different cell types are best studied by means of isolated intact cells. Basic functions of the liver — e.g., the uptake and metabolism of xenobiotics, the maintenance of blood glucose homeostasis, the

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Book 1986ependent on oxidative metabolism, whereas those around the central vein (pericentral, perivenous, or centrolobular areas) are more dependent upon an anaerobic mechanism. Throughout this volume the latter three terms are used synonymously by various authors to indicate the five to eight layers of cel