Titlebook: Regenerative Rehabilitation; From Basic Science t Sarah M. Greising,Jarrod A. Call Book 2022 The American Physiological Society 2022 Injury

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Novel Cell-Based Therapeutics for Diseases of the Heart and Skeletal Muscle,o contemporary medical approaches, which rarely address the root pathogenesis. Regenerative medicine is a specialized field focused on replacing or repairing damaged tissue, which is otherwise incapable of self-healing. For more than four decades, stem and progenitor cells have been recognized for t

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Regenerative Rehabilitation Strategies for Complex Bone Injuries,er comorbidities such as diabetes. The intricacies and poor functional outcomes of these injuries merit the consideration of regenerative medicine in concert with rehabilitation strategies to improve healing. The field of regenerative rehabilitation is emerging with promising technologies, since bon

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Ultrasound Stimulation of Tendon Healing: Current Strategies and Opportunities for Novel Therapeutiealing is crucial to the development of new therapeutic strategies for tendon healing. Tendons do not possess a robust, intrinsic healing response, and conservative and surgical treatments have shown limited efficacy. For chronic tendon injuries (tendinopathies), the principal treatment of choice is

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Mechanical Stimulation as Both the Cause and the Cure of Tendon and Ligament Injuries,ing structural and mechanical deficits often lead to pain, dysfunction, and an increased risk of reinjury. To improve both injury prevention and treatment, it is necessary to better understand the etiology of tendon/ligament injury and the factors that inhibit recovery and healing. Given that the pr

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Methods to Enhance the Beneficial Effects of Exercise in Individuals with Spinal Cord Injuries,ary behavior. This lesser energy expenditure leads to increased fat mass, decreased lean tissue mass, increased body mass index, declines in cardiac structure and function, reduced insulin sensitivity, and lower cardiorespiratory fitness. Collectively these physiological changes increase the risk of

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Emerging Approaches for Regenerative Rehabilitation Following Traumatic Brain Injury,brain as well as the chronic disabilities and ongoing pathologies of various injury endophenotypes. A large body of previous work has shown that traditional rehabilitative therapies in combination with dietary modifications and regular exercise can enhance brain plasticity and, in some cases, neurog

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Book 2022ues. At its core, the primary goal of regenerative rehabilitation is to restore function after damage to bones, skeletal muscles, cartilage, ligaments/tendons, or tissues of the central and peripheral nervous systems. The authors describe the physiology of these neuro- and musculoskeletal tissue typ

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Book 2022apacity. As a result, readers will learn how regenerative rehabilitation exploits that quality, to trigger positive changes in tissue function.. .Combining basic, translational, and clinical aspects of the topic, the book offers a valuable resource for both scientists and clinicians in the regenerative rehabilitation field..

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Regenerative Rehabilitation for Duchenne Muscular Dystrophy,le weakness and dysfunction in DMD, with evidence supporting rehabilitation as an adjunct treatment to gene- and cell-mediated therapies. This chapter summarizes the current state of research for DMD therapy and explores the potential for combined regenerative and rehabilitation therapies to improve outcomes for DMD patients.