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Titlebook: Redox Signaling and Biomarkers in Ageing; Ufuk Çakatay Book 2022 The Editor(s) (if applicable) and The Author(s), under exclusive license

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书目名称Redox Signaling and Biomarkers in Ageing
编辑Ufuk Çakatay
视频video
概述Attracts the attention of a wide group of readership incl. gerontologists, geriatricians, and medical specialists.Brings current research evidence and knowledge on redox signaling and biomarkers in ag
丛书名称Healthy Ageing and Longevity
图书封面Titlebook: Redox Signaling and Biomarkers in Ageing;  Ufuk Çakatay Book 2022 The Editor(s) (if applicable) and The Author(s), under exclusive license
描述.This book aims to present the age-related alterations in redox signaling networks and their diagnostic biomarkers in aging cells using multidisciplinary approach. Establishing sensitive and specific biomarkers of dynamic redox homeostasis is crucially important in the development of effective antiaging and senolytic interventions. Recent years have seen tremendous advances in the understanding of redox signaling events which highlight the process of aging and age-related pathologies. A major challenge in biological aging research is developing reliable biomarkers to determine the consequences of disrupted redox signaling networks long before the clinical diagnosis of age-related diseases is made. Therefore, we have chosen to concentrate on aging-induced aberrant redox signaling networks, their biomarkers, and pathological consequences in this book...Although oxidation is a natural metabolic process, the imbalance in the level of oxidants and antioxidants causes oxidative stress and eventually leads to inflammatory conditions, diabetes, neurodegenerative diseases, and cancer. Novel redox-sensitive biomarkers for the evaluation of aging-induced proteinopathies such as amyloid ß and
出版日期Book 2022
关键词Redox homeostasis; Redox imbalance; Redox signaling; Redox status biomarkers; Aging related signaling; Ag
版次1
doihttps://doi.org/10.1007/978-3-030-84965-8
isbn_softcover978-3-030-84967-2
isbn_ebook978-3-030-84965-8Series ISSN 2199-9007 Series E-ISSN 2199-9015
issn_series 2199-9007
copyrightThe Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Switzerl
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Impaired Redox Homeostasis and Cardiovascular Agingy demand. Furthermore, we provide a brief overview of several anti-inflammatory and/or antioxidative substances such as statins, colchicine, canakinumab, and vitamins and briefly present the evidence from experimental studies and randomized controlled trials regarding the utility of these substances
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Redox Homeostasis in Skeletal Muscle Aginglife extension which inconclusively provides debate of ROS-induced aging and diseases. Skeletal muscle loss is one of the major hallmarks of aging and ROS, and oxidative stress is considered to be the main cause of skeletal muscle aging. This chapter discusses how ROS can influence the aging of skel
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Aging and Exercise-Induced Reactive Oxygen Speciesallows the cells to adapt to exercise-induced stress within individual physiological limits. Thus, regular antioxidant supplementation might be beneficial for the elderly with regards to exercise performance. Albeit redox homeostasis is fundamentally related to aerobic type of exercise, anaerobic ex
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Redox Signalling, Autophagy and Ageing etiology of ageing, and the cellular machinery that regulates redox, autophagy and ageing has been elucidated. Redox signalling orchestrates autophagy and ageing processes leading to altered transduction of redox homeostasis. This chapter discusses ageing process, generation of ROS, redox signallin
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Modulation of Redox and Aging-Related Signaling Pathways and Biomarkers by Naturally Derived Peptidelifespan. As oxidative stress resistance is conveniently used as a prognostic indicator of anti-aging capability, a number of natural peptides are also shown to promote longevity in . and .. The antioxidant and anti-aging activities of peptides are found to involve a range of evolutionarily conserve
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