Titlebook: Recognition of M. leprae antigens; Tom Ottenhoff,René Vries Book 1987 Martinus Nijhoff Publishers, Dordrecht 1987 Antigen.Lepra.T cell.cel

sed-rate

, Specific Protein Antigens Defined by Cloned Human Helper T Cells,. (1). At one pole of this spectrum are lepromatous leprosy patients showing a .. . specific T cell unresponsiveness (2); at the other pole are tuberculoid leprosy patients displaying both acquired immunity and delayed type hypersensitivity against .. . which are thought to be conferred by helper T

Obstruction

Cloned Suppressor T Cells from a Lepromatous Leprosy Patient Suppress , Reactive Helper T Cells,ng with the cellular immune responsiveness of the patient (1): at one pole of this spectrum are tuberculoid patients displaying both acquired cellmediated immunity and delayed type hypersensitivity against the bacillus (2–4). At the other pole are lepromatous patients which show a specific T cell un

伴随而来

Terrace

多骨

Ophthalmologist

lavish

appall

MHC Class II Ir/Is Gene Controlled Antigen Specific T Cell Activation and Disease Susceptibility: Lr and Is genes. The final section of this chapter describes the different clinical manifestations of leprosy, the major immuneregulatory disturbances in the disease and the role of HLA linked (Ir and Is) genes in controlling the type of immune responsiveness and thus the type of leprosy that is mounted by the host against ..

损坏

HLA-DR3 Molecules are the Products of an HLA Class II Immune Regulator Gene for , Predisposing to Ten receptor repertoire b) differences in the capacity of class II molecules to associate with antigen in order to create an immunogenic complex for T cells, and c) differences in the activation of functionally distinct T cell compartments, e.g. suppressor (Ts) versus helper (Th) cells (2,3).

Perineum

General Discussion: , Specific Activation of Helper and Suppressor T Cells and its Regulation by HLr lepromatous leprosy (LL) with numerous progressive lesions and .. . specific T cell unresponsiveness, presumably as a consequence of .. . specific suppression (1). In between those two poles variable degrees of tuberculoid or lepromatous features can be found in borderline leprosy patients (1).