Titlebook: Recent Trends in Cancer Biology: Spotlight on Signaling Cascades and microRNAs; Cell Signaling Pathw Sundas Fayyaz,Ammad Ahmad Farooqi Book

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,TGF-β/Smad Signalling Pathway in Cancer,tional in development of cancer. In early stages of tumour development, TGF-β plays tumour suppressive, and as tumour progressed, TGF-β is an oncogenic factor. Functioning as tumour suppressor, TGF-β is a potential growth inhibitor. Cancerous cells show high sensitivity to TGF-β inhibition either by

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Sebaceous Carcinoma of the Eyelid,25%. Historical studies have shown that mortality rates could be as high as 83%, but with the advent of increased detection, diagnosis, and treatment options, mortality rates have dropped substantially. A major issue with obtaining a proper diagnosis of SC is that it can mimic many other benign and

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The Crosstalk Between miRNAs and Autophagy in Cancer Progression,ion of miRNAs is linked to many human diseases including cancer. Impaired levels of miRNAs may also result in defected autophagy. Autophagy is a double-edged sword during cancer initiation and progression. At the beginning of tumorigenesis, autophagy suppresses tumor formation by removing defective

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Role of CEACAM in Different Cancers,pment and progression. The greatest stumbling block in improving the clinical outcome of cancer patients is that tumors continuously adapt to their micro-environment and evolve ways to develop resistance against molecular therapeutics. We are developing systems-level understanding of tumors about th

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