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Titlebook: Recent Trends in Cancer Biology: Spotlight on Signaling Cascades and microRNAs; Cell Signaling Pathw Sundas Fayyaz,Ammad Ahmad Farooqi Book

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发表于 2025-3-21 19:01:50 | 显示全部楼层 |阅读模式
书目名称Recent Trends in Cancer Biology: Spotlight on Signaling Cascades and microRNAs
副标题Cell Signaling Pathw
编辑Sundas Fayyaz,Ammad Ahmad Farooqi
视频videohttp://file.papertrans.cn/824/823403/823403.mp4
概述Features cutting-edge coverage and translational perspective;.Provides mechanistic insights and most recent ‘bench to bedside and back’ breakthroughs;.Different chapters of the book are written by an
图书封面Titlebook: Recent Trends in Cancer Biology: Spotlight on Signaling Cascades and microRNAs; Cell Signaling Pathw Sundas Fayyaz,Ammad Ahmad Farooqi Book
描述Cancer is a multifaceted disease and overwhelmingly increasing experimental evidence has helped us to develop a deeper understanding of the role of signal transduction cascades in cancer development and progression. Tissue microarrays and next generation sequencing technologies have assisted us to gather missing pieces of jigsaw puzzle and we now know that deregulation of spatio-temporally controlled signaling cascades play fundamental role in metastasis and resistance against wide ranging therapeutics..This book offers a balanced overview of the rapidly emerging cutting edge research in molecular oncology and good source of knowledge for established oncologists, basic and medical students and pharmaceutical industry associated R&D departments..
出版日期Book 2018
关键词Signaling Cascades; Molecular Oncology; Cancer Development and Progression; Signal Transduction; microRN
版次1
doihttps://doi.org/10.1007/978-3-319-71553-7
isbn_softcover978-3-030-10074-2
isbn_ebook978-3-319-71553-7
copyrightSpringer International Publishing AG, part of Springer Nature 2018
The information of publication is updating

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When the Molecules Start Playing Chess, or How MicroRNAs Acquire Dualistic Activity During Cancer Ppressor microRNAs into tumor promoting omcomiRs. Understanding mechanics of this dualism will reveal how far tumor progression could go. This chapter will discuss some aspects of the current knowledge and understanding of this side of oncogenesis.
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From Endometriosis to Cancer: Spotlight on Intracellular Signaling Cascades and MicroRNAs,ways promote transformations from benign to premalignant endometriosis. It is becoming progressively more understandable that genetic/epigenetic mutations, inactivation of tumor suppressors, aberrant expression of different microRNAs play decisive role in malignant transformation of endometriosis.
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Tyrosine Kinases, microRNAs, Epigenetics: New Insights in the Mechanisms of Leukemogenesis,tudies have contributed to deepen the knowledge of the mechanisms underlying leukemogenesis. Interestingly, different types of leukemias may share the same molecular abnormality (for example, the loss of the . gene). Conversely, only few haematological malignancies harbour a single and specific aber
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Tranquilizing and Awakening ATM to Promote Killing of Cancer Cells, sources. To overcome these stumbling blocks, cells have evolved a global DNA damage response (DDR), which is an intricate and hierarchically organized network of interweaved pathways that are “switched on” whenever genotoxic insults occurs. ATM, ATR, and DNA-PK are multitalented modulators of DNA d
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Bone Cancer: Dysregulation of Signaling Cascades by microRNAs,nd osteocyte cells. Complex regulatory networks are required during these events in osteogenesis, and their imbalance can cause disastrous disordering and consequently diseases, such as cancer. Bone-related diseases involve a deregulation of genes, microRNAs, transcription factors (TF) or proteins i
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The Roles of miR-25 and Its Targeted Genes in Human Cancer,s. miRNAs are small non-coding RNAs that regulate gene expression by targeting messenger RNAs for translational repression or, at lesser extent, mRNAs degradation. Within the several functions controlled by miRNAs there are the control of cell proliferation, apoptosis, differentiation, cell migratio
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