Titlebook: Recent Progress in the Genetic Epidemiology of Cancer; Henry T. Lynch (Professor of Medicine, Professor a Conference proceedings 1991 Spri

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洞察力

obtuse

临时抱佛脚

Ascertainment Problems in Family Data: Methodological Aspectshe males children with different females. Often the term may refer to a pedigree over more than two generations. In social sciences the term “family” may denote a household, whose members are not necessarily related.

browbeat

Overdose

Linkage Mapping of Cancer Susceptibility Genesudy of complex diseases such as behavioural traits and inherited predisposition to common cancers. While the difficulties associated with mapping complex traits or diseases are more daunting, the potential impact on public health of unravelling their genetics readily warrants the change of focus.

在驾驶

Search for Genetic Factors in the Etiology of Breast Cancerioncogenes or, more appropriately, tumor suppressor genes. The finding that a genetic change as little as a single point-mutation can distinguish the normal constitutional homologue of c-Ha-. from its tumorigenic counterpart (Bos 1989) still stands as a paradigm for the role of gene mutation in tumorigenesis.

Panther

Pitfalls and Prospects in Genetic Epidemiology of Cancerhan then, his remark that “there is no faster way to dull the edge of the beautiful mathematical tools which we now possess than to attempt to use these tools in inappropriate situations” is pertinent. My experience with some of these pitfalls has been intimate and painful. I describe them in the hope that others may avoid them.

增长

的阐明