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Titlebook: Recent Progress in the Chemical Synthesis of Antibiotics; G. Lukacs (Directeur de Recherche C.N.R.S.),M. Ohn Book 1990 Springer-Verlag Ber

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Actinobolin and Bactobolin: Chemical Aspects and Syntheses,uction. If the natural product is complex, because of the presence of delicate functional groups and/or myriad chiral centers, the challenge becomes virtually irresistible. If the material displays biological activity, organic chemists will succumb to the challenge, and in time, a synthesis will be
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Total Synthesis of Lincomycin and Related Chemistry,f the antibiotic lincomycin. In the first part we present total syntheses of lincosamine that start from carbohydrate precursors. The D-galactose-derived aldehyde is the most frequently used synthon. In the second part, total syntheses of lincosamine from non-carbohydrate precursors are presented. T
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Synthetic Study on Man-Made Bleomycins Based on the Anticancer Mechanism of Natural Bleomycins,.-β-Hydroxy-.-histidine, a novel amino acid constituent of BLM and a pivotal amino acid for the biological activity, has been prepared based on the stereocontrolled aldol strategy using chiral 1,3-oxazolidin-2-one auxiliary. In order to study the biochemical functions of BLM, model compounds have be
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