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Titlebook: Recent Developments in Prophylactic Immunization; A. J. Zuckerman Book 1989 Kluwer Academic Publishers 1989 AIDS.bacteria.infection.molecu

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Chemical synthesis of hepatitis B vaccine,of infected people lead to a chronic carrier state. The number of chronic carriers of the virus throughout the world is considered to be 280 million (Figure 1). The hepatitis B carrier state leads at high frequency to primary hepatocellular carcinoma (~1 million new cases per year) representing a ma
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Prospects of immunization against EB virus,er virus, and the recently discovered human herpesvirus 6. As with all the viruses in this group the structure of EB virus is relatively complex. It consists of an outer, cell-derived, lipid membrane carrying several virus-coded glycoproteins of 340, 220 and 85 kd (gp340, gp220, gp85). surrounding a
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The development of vaccines against AIDS,V).. The true incidence of this disease is not known accurately, but the reported cases worldwide continue to accumulate at an ever-increasing rate. Epidemiological surveys indicate that there will be at least 1 million new cases of AIDS within the next 5 years. Clearly, the AIDS pandemic needs to b
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Prospects for the development of a vaccine for schistosomiasis,to infection. The disease has widespread distribution in Africa and the Middle East (. and .) and in the Western hemisphere (Brazil, Venezuela, Surinam and certain Caribbean islands) for .. In the Far East, China the Philippines and Indonesia are endemic areas of . and limited foci have also been re
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Recombinant vaccinia virus vaccines,ontinued, in the future vaccinia virus might be reused as a live vaccine but against other medical or veterinary pathogens. This possibility arises due to advances in molecular genetics that enable the construction of vaccinia virus recombinants which express antigens derived from other pathogens. I
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, immunization,agents. . has emerged as one of the most common and most problematic among these modern opportunistic pathogens.. Perhaps of most concern has been the unusually high mortality associated with . bacteraemia and pneumonia, often twice that observed with other Gram-negative bacillary infections..
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Rabies vaccines, occur annually. Rabies is prevalent throughout most of the world and many millions of doses of vaccine are given each year following genuine or possible exposures to the virus. Comparatively little is given for pre-exposure prophylaxis.
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