Titlebook: Recent Developments in Prophylactic Immunization; A. J. Zuckerman Book 1989 Kluwer Academic Publishers 1989 AIDS.bacteria.infection.molecu

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nization". This is well illustrated by the WHO Expanded Programme on Immunization (EPI) which in developing countries is now preventing nearly a million deaths annually from measles, pertussis and neonatal tetanus, and for which there is a commitment by the WHO and UNICEF to protect all children by

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Immunization against leprosy,igh priority. Ten years later, trials are under way of the approaches they identified, namely, vaccines based on antigenically similar cultivatable mycobacteria, killed ., or of a mixture of killed . with BCG. This chapter will discuss the rationale for such vaccines, together with the possibility o

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The application of molecular biology to the development of new vaccines against poliomyelitis,cated molecular biological and immunological techniques to the study of this virus has provided detailed insights into its molecular and genetic structure, its mode of replication and the molecular basis of its pathogenicity (for reviews see refs 1–3). Poliomyelitis, the disease caused by the poliov

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