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Titlebook: Recent Developments in Alcoholism; Volume 2 Marc Galanter,Henri Begleiter,David Theil Book 1984 Plenum Press, New York 1984 Syndrom.attenti

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楼主: Diverticulum
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Hypermetabolic State and Hypoxic Liver Damageeneral, limited by the rate at which mitochondria can reoxidize reducing equivalents and thus by the rate at which oxygen can be consumed by the liver. This relationship appears to be most important in conditions in which the alcohol dehydrogenase (ADH)/Q(>2 ratio is high and is not in conflict with
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Commentary on the Hypermetabolic State and the Role of Oxygen in Alcohol-Induced Liver Injuryic ethanol ingestion in rodents results in increased hepatic oxygen consumption and in a steeper fall in oxygen tension between the periportal and the pericentral area of the lobule, rendering the pericentral area susceptible to hypoxia. Hepatocellular necrosis occurs when ethanol-fed animals are ex
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Alcohol-Induced Mitochondrial Changes in the Liverions and morphology of the mitochondria. Morphologically, the changes observed in human alcoholics and experimental animals appear similar. Bizarrely shaped mitochondria and megamitochondria are detected at the fatty liver stage and persist as the disease progresses. As yet, however, no correlation
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Neurobiological Relationships between Aging and Alcohol Abuseh molecular changes that in turn alter electrophysiology and morphology and finally culminate in changes of behavior (individual and social) are largely unknown. While these chains originating with molecular events leading to the same behavioral end result may be totally different, they may also ove
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Alcohol Consumption and Premature Agingl, electrophysiological, and regional blood flow measures of brain function. These similarities have led to speculation that excessive alcohol consumption causes a premature aging of the brain that, in turn, is responsible for the characteristic structural and functional changes seen in detoxified a
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Life Stressors and Problem Drinking among Older Adultsdefining problem drinking in this population is pointed out. We critically examine the empirical evidence relating life stressors (e.g., death of a spouse) to the onset of problem drinking in older age and, to a lesser extent, to the continuation of drinking problems into the later stages of the lif
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Cross-Cultural Aspects of Alcoholism in the Elderly common features across cultures. These include an inverse relationship between age and problem-producing dosages, increased risk of elderly alcoholics to trauma, greater efficacy of milieu changes with age, and a concentration of elderly alcoholics in cities. Conversely, certain other aspects of ag
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