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Titlebook: Recent Advances In Retinal Degeneration; Robert E. Anderson,Matthew M. LaVail,Joe G. Hollyf Book 2008 The Editor(s) (if applicable) and Th

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In vitro Analysis of Ribozyme-mediated Knockdown of an ADRP Associated Rhodopsin MutationSung et al., 1993; Sung et al., 1991), rhodopsin mutations that are similar to wild-type in terms of expression levels, folding and formation of functional photopigment are considered Class 1 mutations.
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Genetic Supplementation of RDS Alleviates a Loss-of-function Phenotype in C214S Model of Retinitis Phang, Garibaldi, Li, Green, & Zack, 2002). As a membrane glycoprotein located in the disc rim region in the OSs of rods and cones (Connell & Molday, 1990; Molday, Hicks, & Molday, 1987; Travis, Brennan, Danielson, Kozak, & Sutcliffe, 1989).
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of the Retina in the 4 Years Following rAAV-mediated Gene Transfer in the RPE65 Null Mutation Dog therapy to morphologic findings up to 4 years following the gene transfer. In addition, retinas of affected dogs were examined for histologic correlates of spots and color changes seen by ophthalmoscopy in both treated and untreated affected dogs.
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0065-2598 t of The International Symposium on Retinal Degeneration which has become perhaps the most important research meeting in the field. The topics in this volume explore the etiology, cellular mechanisms, epidemiology, generics, models and potential therapeutic measures for the blinding diseases of reti
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Curing Blindness with Stem Cells: Hope, Reality, and Challenges which the author presented his personal views of the contributions that the study of retinal cell differentiation during normal embryonic development can make towards overcoming the limitations that have so far prevented curing blindness through stem cell transplantation. The talk was illustratedma
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Retinal Degenerations: Planning for the Future95; Attebo et al., 1996; Klaver et al., 1998; Novak-Laus et al., 2002). In the United States an estimated 6 million people have age-related macular degeneration with a decrease in central vision after age 60. About 100,000 people have retinitis pigmentosa or a related disease with loss of side and n
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On the Role of CNTF as a Pontential Therapy for Retinal Degeneration: Dr. Jekyll or Mr. Hyde?. CNTF was initially isolated from the chick eye as a soluble factor that promotes the survival of dissociated ciliary ganglionic neurons of 12-day chick embryos (Adler et al., 1979). Its use as a neuroprotective agent for the retina was first tested in rats 15 years ago in a light-damage model of r
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