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Titlebook: Recent Advances In Retinal Degeneration; Robert E. Anderson,Matthew M. LaVail,Joe G. Hollyf Book 2008 The Editor(s) (if applicable) and Th

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发表于 2025-3-21 18:29:28 | 显示全部楼层 |阅读模式
书目名称Recent Advances In Retinal Degeneration
编辑Robert E. Anderson,Matthew M. LaVail,Joe G. Hollyf
视频video
概述Special focus on mechanism of photoreceptor degeneration and cell death.Includes supplementary material:
丛书名称Advances in Experimental Medicine and Biology
图书封面Titlebook: Recent Advances In Retinal Degeneration;  Robert E. Anderson,Matthew M. LaVail,Joe G. Hollyf Book 2008 The Editor(s) (if applicable) and Th
描述.Retinal Degenerations is the result of The International Symposium on Retinal Degeneration which has become perhaps the most important research meeting in the field. The topics in this volume explore the etiology, cellular mechanisms, epidemiology, generics, models and potential therapeutic measures for the blinding diseases of retinitis pigmentosa and age-related macular degeneration...Special focus is highlighted in the areas of Mechanisms of Photoreceptor Degeneration and Cell Death (extremely important because very little is known how or why photoreceptors die in these diseases, despite an abundance of genetic information), Age-Related Macular Degeneration (with several novel approaches to its analysis), Usher Syndrome (the most severe form of retinitis pigmentosa, which includes an early of congenital loss of hearing along with blindness), and Gene Therapy. In addition, the section on Basic Science Related to Retinal Degeneration is particularly strong with several laboratories reporting on new discoveries in the area of outer segment phagocytosis, a key component of photoreceptor-retinal pigment epithelial cell interactions in normal and degenerating retinas. .
出版日期Book 2008
关键词development; diseases; endothelium; etiology; gene expression; genetics; hearing; inflammation; macular dege
版次1
doihttps://doi.org/10.1007/978-0-387-74904-4
isbn_softcover978-1-4419-2577-0
isbn_ebook978-0-387-74904-4Series ISSN 0065-2598 Series E-ISSN 2214-8019
issn_series 0065-2598
copyrightThe Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Science+Busines
The information of publication is updating

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https://doi.org/10.1007/978-0-387-74904-4development; diseases; endothelium; etiology; gene expression; genetics; hearing; inflammation; macular dege
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Robert E. Anderson,Matthew M. LaVail,Joe G. HollyfSpecial focus on mechanism of photoreceptor degeneration and cell death.Includes supplementary material:
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Development of Viral Vectors with Optimal Transgene Expression for Ocular Gene Therapiesrapies using viral vectors are one of the promising technologies. For an ideal therapeutic effect, a variety of vector designs have been tested. Especially, selection of a promoter to drive a transgene is important to obtain adequate level of expression. In this brief chapter, reviewed are the promoters for viral vectors for ocular gene therapies.
发表于 2025-3-22 22:23:36 | 显示全部楼层
Curing Blindness with Stem Cells: Hope, Reality, and Challengesta, 2001; Hatakeyama and Kageyama, 2004; Jean et al., 1998; Livesey and Cepko, 2001; Lupo et al., 2000; Malicki, 2004; Marquardt and Gruss, 2002; Rapaport et al., 2004; Vetter and Brown, 2001; Zhang et al., 2002).
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Nanoceria Particles Prevent ROI-Induced Blindnesside, hypochlorite ions, hydroxyl radicals, hydroxyl ions and superoxide anions (Beatty et al., 2000), react with almost any nearby DNA, RNA, lipid, carbohydrate or protein. They are produced primarily by the normal oxidative metabolism that occurs in the mitochondrial respiratory chain.
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