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Titlebook: Recent Advances in Drug Delivery Systems; James M. Anderson,Sung Wan Kim Book 1984 Plenum Press, New York 1984 Insulin.Motivation.antibiot

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Development of Encapsulated Antibiotics for Topical Administration to Wounds,improve methods of treating these wounds and to prevent infection, antibiotics microencapsulated in poly(DL-lactide-co-glycolide) (DL-PLG) have been formulated to release drug at a controlled rate over an extended period. The microcapsules are applied topically to open contaminated wounds so that th
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Albumin Microspheres for Intraarterial Drug Targeting,ng of such compounds to target areas, liposomes, nanoparticles and microspheres have been suggested. Since organ distribution of the latter is dependent upon their size and shape, it is reasonable to attempt second order (1) targeting of microspheres on this basis. This contribution gives our result
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A Bioresponsive Membrane for Insulin Delivery,ystem. Insulin levels are higher than normal immediately after injection but are below normal levels at any other times, and glucose levels are correspondingly abnormal. Many degenerative conditions associated with diabetes (e.g., increased vascular disease, impairment of kidney function and vision)
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Drug Release from Matrix Devices,n a polymer network. Within this context at least four different types of devices can be envisioned. These include: i) dissolved matrix devices wherein the drug is dissolved within a crosslinked polymer at or below the saturation solubility of drug in the polymer; ii) dispersed matrix devices in whi
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Controlled Release and Magnetically Modulated Systems for Macromolecules: Recent Advances,olecules (M.W.> 1000) (1), these systems have been used by different investigators in many areas of research (2–21). Macromolecules such as enzymes (22), antigens (23) and insulin (24) have been released in biologically active form for up to six months ... Extensive studies .. have demonstrated that
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Release of Bioactive Agents from Swellable Polymers: Theory and Experiments,lease systems for pharmaceutical applications. Langer and Peppas (1–3) and Peppas and Gurny (4) have reviewed various aspects of the preparation, structure and biocompatibility of polymers for pharmaceutical applications and have established methods for incorporation of drugs in and kinetic behavior
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Tissue Responses to Drug Delivery Systems,issue reaction which surrounds the implant. The second parameter is the absorption of the drug into the local tissue environment and the role that this phenomenon plays in determining the serum and organ levels of the drug at any given time following administration.
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