| 书目名称 | Recent Advances in Cell Biology of Acute Leukemia |
| 副标题 | Impact on Clinical D |
| 编辑 | Wolf-Dieter Ludwig,Eckhard Thiel |
| 视频video | |
| 丛书名称 | Recent Results in Cancer Research |
| 图书封面 |  |
| 描述 | The development of new techniques such as immuno phenotyping, cytogenetic investigations and, more recently, molecular studies has considerably increased our diagnostic repertoire and broadened our ideas about the biology of acute leukemias. While immunophenotyping with mono clonal antibodies has yielded increased diagnostic precision and made it possible to develop a highly reproducible classification of acute leukemias based on cell-biological features, further insights have been gained into the patho genetic mechanisms involved in leukemogenesis by means of cytogenetic detection of acquired structural chromosomal abnormalities. Analysis of the leukemia-associated chromo somal breakpoints using molecular techniques can now pinpoint many genomic sites essential for normal develop ment and maturation of hematopoietic cells but functionally disrupted in leukemic cells. The main goal of the international workshop that we held in Berlin with a select group of scientists and clinicians involved in leukemia research was to describe the state of the art and new developments in the immunologic, cytogenetic, and molecular characterization of acute leukemias and to discuss the clinical |
| 出版日期 | Conference proceedings 1993 |
| 关键词 | Acute Leukemia; Akute Leukämien; Antigen; Cytogenetics; Immunophenotype; Immunphänotype; Molecular-cell bi |
| 版次 | 1 |
| doi | https://doi.org/10.1007/978-3-642-84895-7 |
| isbn_softcover | 978-3-642-84897-1 |
| isbn_ebook | 978-3-642-84895-7Series ISSN 0080-0015 Series E-ISSN 2197-6767 |
| issn_series | 0080-0015 |
| copyright | Springer-Verlag Berlin Heidelberg 1993 |
发表于 2025-3-21 17:17:33
