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Titlebook: Recent Advances in Cell Biology of Acute Leukemia; Impact on Clinical D Wolf-Dieter Ludwig,Eckhard Thiel Conference proceedings 1993 Spring

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Conference proceedings 1993ased our diagnostic repertoire and broadened our ideas about the biology of acute leukemias. While immunophenotyping with mono­ clonal antibodies has yielded increased diagnostic precision and made it possible to develop a highly reproducible classification of acute leukemias based on cell-biologica
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Contribution of Electron Microscopy to the Classification of Minimally Differentiated Acute Leukemiapeared to provide information to diagnose conclusively cases of minimally differentiated acute myeloid leukemia’s (AML M0; Bennett et al. 1991) and acute megakaryoblastic leukemia (AML M7; Bennett et al. 1985).
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Immunophenotypic and Immunogenotypic Detection of Minimal Residual Disease in Acute Lymphoblastic Leues for the detection of low numbers of leukemic cells are needed to obtain better insight into the reduction of tumor mass during induction treatment and further eradication of the leukemic cells during maintenance treatment.
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Myeloid-Associated Antigen Expression in Childhood Acute Lymphoblastic Leukemiats a high-risk group as demonstrated by fewer complete remissions and shorter survival time (Sobol et al. 1987; Childs et al. 1989). This prospective study of childhood ALL reports clinical features and treatment outcome in relation to myeloid-associated antigen expression.
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0080-0015 ably increased our diagnostic repertoire and broadened our ideas about the biology of acute leukemias. While immunophenotyping with mono­ clonal antibodies has yielded increased diagnostic precision and made it possible to develop a highly reproducible classification of acute leukemias based on cell
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Preclinical Studies of T-Cell-Mediated Immune Responses Against Autologous Tumor Cells in Patients wRisk-adapted therapy in patients with acute leukemia has significantly improved prognosis. As a result of relapsing disease and increasing resistance to chemotherapy, however, long-term survival in nontransplanted patients does not exceed 30% (Büchner et al. 1985). Clearly, new therapeutic approaches are needed.
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