| 书目名称 | Reactive Oxygen Species |
| 副标题 | Network Pharmacology |
| 编辑 | Harald H. H. W. Schmidt,Pietro Ghezzi,Antonio Cuad |
| 视频video | |
| 概述 | This book is a game changer for the field and many clinical areas such as cardiology and neurology.Suggests a new approach to reactive oxygen species (ROS) and opens a new chapter in redox medicine.Le |
| 丛书名称 | Handbook of Experimental Pharmacology |
| 图书封面 |  |
| 描述 | . .Reactive oxygen species (ROS) have been implicated in almost every human disease phenotype, without much, if any, therapeutic consequence foremost exemplified by the failure of the so-called anti-oxidants. This book is a game changer for the field and many clinical areas such as cardiology and neurology. The term ‘oxidative stress’ is abandoned and replaced with a systems medicine and network pharmacology-based mechanistic approach to disease. The ROS-related drugs discussed here target either ROS- forming or ROS -modifying enzymes for which there is strong clinical evidence. In addition, ROS targets are included as they jointly participate in causal mechanisms of disease. This approach is transforming the ROS field and represents a breakthrough in redox medicine indicating a path to patient benefit. In the coming years more targets and drugs may be discovered, but the approach will remain the same and this book will thus become, and for many years remain, the leadingreference for ROSopathies and their treatment by network pharmacology. . .Chapter "Soluble Guanylate Cyclase Stimulators and Activators" is available open access under a Creative Commons Attribution 4.0 Internation |
| 出版日期 | Book 2021 |
| 关键词 | reactive oxygen species (ROS); systems medicine; ROS targets; network pharmacology; signalling pathways |
| 版次 | 1 |
| doi | https://doi.org/10.1007/978-3-030-68510-2 |
| isbn_softcover | 978-3-030-68512-6 |
| isbn_ebook | 978-3-030-68510-2Series ISSN 0171-2004 Series E-ISSN 1865-0325 |
| issn_series | 0171-2004 |
| copyright | Springer Nature Switzerland AG 2021 |
发表于 2025-3-21 19:13:08
