书目名称 | Rat Genomics | 副标题 | Methods and Protocol | 编辑 | Ignacio Anegon | 视频video | | 概述 | Comprehensive and an easily accessible reference volume for developing, running, and analyzing biomedical research using the rat as model system.Includes supplementary material: | 丛书名称 | Methods in Molecular Biology | 图书封面 |  | 描述 | .Grown exponentially by the genomic revolution, the use of the rat as a model of choice for physiological studies continues in popularity and at a much greater depth of understanding. In .Rat Genomics: Methods and Protocols., world-wide experts provide both practical information for researchers involved in genomic research in the rat along with a more contextual discussion about the usefulness of the rat in physiological or translational research in different organs and systems. The volume extensively covers topics including genome sequencing, quantitative trait loci mapping, and the identification of single nucleotide polymorphisms as well as the development of transgenic technologies such as nuclear cloning, lentiviral-mediated transgenesis, gene knock-down using RNA interference, gene knock-out by mutagenesis, and zinc finger nucleases plus exciting advances in the obtention of rat embryonic cell lines. As a volume in the highly successful .Methods in Molecular Biology.™ series, this work provides the kind of detailed description and implementation advice that is crucial for getting optimal results...Comprehensive and up-to-date, .Rat Genomics: Methods and Protocols. thoroughly | 出版日期 | Book 2010 | 关键词 | BAC; DNA; Microarray; PCR; Promoter; Quantitative PCR; Single Nucleotide Polymorphism; Translation; YAC; cell | 版次 | 1 | doi | https://doi.org/10.1007/978-1-60327-389-3 | isbn_softcover | 978-1-61779-686-9 | isbn_ebook | 978-1-60327-389-3Series ISSN 1064-3745 Series E-ISSN 1940-6029 | issn_series | 1064-3745 | copyright | Humana Press 2010 |
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