书目名称 | Ras Signaling | 副标题 | Methods and Protocol | 编辑 | Lorenza Trabalzini,Saverio Francesco Retta | 视频video | | 概述 | Includes experimental approaches to the complexity of the biological functions of RasGTPases.Provides step-by-step detail essential for reproducible results.Contains key notes and implementation advic | 丛书名称 | Methods in Molecular Biology | 图书封面 |  | 描述 | .Featuring experimental approaches that shed light on the complexity of Ras GTPase biological functions, .Ras Signaling: Methods and Protocols. contains general overviews and detailed applications of both well-established and recently developed research techniques, including biochemical, biophysical, molecular biology, genetic and behavioral approaches, advanced high resolution fluorescence and electron microscopy imaging and “omics” technologies. Through this, the detailed volume provides information on expression, post-translational modifications, subcellular localization and dynamics, regulatory mechanisms of upstream and downstream signaling pathways and ultimately, biological activities and functions of Ras GTPases in different model systems, including high and low eukaryotic organisms. Written in the highly successful .Methods in Molecular Biology. series format, chapters include brief introductions, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols and tips on troubleshooting and avoiding known pitfalls..Wide-ranging and authoritative, .Ras Signaling: Methods and Protocols. serves as an aid for investigators of different b | 出版日期 | Book 2014 | 关键词 | Cell signaling; GTP-binding and hydrolyzing proteins; Model systems; Pathological condition treatment; R | 版次 | 1 | doi | https://doi.org/10.1007/978-1-62703-791-4 | isbn_softcover | 978-1-4939-6054-5 | isbn_ebook | 978-1-62703-791-4Series ISSN 1064-3745 Series E-ISSN 1940-6029 | issn_series | 1064-3745 | copyright | Springer Science+Business Media, LLC 2014 |
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