Titlebook: Radiotherapy in Managing Brain Metastases; A Case-Based Approac Yoshiya Yamada,Eric Chang,Jonathan Knisely Book 2020 Springer Nature Switze

Mechanics

Introduction,The development of stereotactic radiosurgery for the treatment of brain metastases has been an evolution of improvements in technology coupled with paradigm shifts in oncology, providing a highly effective therapy for an otherwise clinically vexing problem. The historical development of this seminal medical innovation is described.

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Pandemic

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978-3-030-43742-8Springer Nature Switzerland AG 2020

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Supportive Medical Management of Brain Metastases Patients Including Treatment Complicationsent. These include focal neurologic deficits, seizures, cognitive impairment, and headache. We will review the data regarding the management of these problems. Iatrogenic sequelae and radiotherapy-related complications such as radiation necrosis will also be specifically addressed.

aggressor

Radiobiology of Stereotactic Radiosurgerynized that the immune system, which plays key roles in tumor surveillance and suppression, is an integral component of the SRS response. In addition to the hypothesis that SBRT may be able to overcome tumor-induced immunosuppression, there is tremendous excitement that SBRT could act synergistically

疏远天际

Indications for Whole-Brain Radiation Therapyive to WBRT in patients with 4–15 metastases, though the results of randomized trials are awaited. Newer systemic therapies such as targeted therapy and immunotherapy have demonstrated relatively high rates of intracranial response for patients with limited intracranial disease, though the optimal s

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