Titlebook: Radiopharmaceutical Chemistry; Jason S. Lewis,Albert D. Windhorst,Brian M. Zeglis Book 2019 Springer Nature Switzerland AG 2019 radiopharm

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Small Molecules as Radiopharmaceutical Vectorsral critical ‘design parameters’ for the creation of effective small molecule radiopharmaceuticals. More specifically, we will discuss an eclectic set of physicochemical and pharmacological properties, guidelines, tolerances, and ‘rules of thumb’ that—when considered together—can assist in the ident

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The Radiopharmaceutical Chemistry of Carbon-11: Basic Principles labeling biologically relevant compounds. Undoubtedly, the most useful of all these secondary precursors is [.C]methyl iodide due to the presence of methylated heteroatoms in many drugs and naturally occurring biomolecules.

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The Radiopharmaceutical Chemistry of the Radionuclides of Gallium and Indium and infection. Finally, gallium-68 typically serves as a radiolabel for small molecules with rapid pharmacokinetic profiles, such as peptides. Both indium-111 and gallium-67 emit Auger electrons as well as photons, leading to their potential use for radionuclide therapy. Chelators and bifunctional

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