找回密码
 To register

QQ登录

只需一步,快速开始

扫一扫,访问微社区

Titlebook: RUNX Proteins in Development and Cancer; Yoram Groner,Yoshiaki Ito,Andre van Wijnen Book 2017 This is a U.S. Government work and not under

[复制链接]
楼主: 柳条筐
发表于 2025-3-25 03:25:06 | 显示全部楼层
Roles of the , Enhancer in Normal Hematopoiesis and Leukemogenesisty of enhancers is tightly regulated in an integrated and combinatorial manner, thus yielding complex patterns of transcription in different tissues. Identifying enhancers is crucial to understanding the physiological and pathogenic roles of their target genes. The . intronic enhancer, eR1, acts in
发表于 2025-3-25 09:48:46 | 显示全部楼层
RUNX1-ETO Leukemiachieved in understanding the molecular pathogenesis of AML1-ETO leukemia. Proteomic surveies have shown that AML-ETO forms a stable complex with several transcription factors, including E proteins. Genome-wide transcriptome and ChIP-seq analyses have revealed the genes directly regulated by AML1-ETO
发表于 2025-3-25 14:16:30 | 显示全部楼层
发表于 2025-3-25 18:25:21 | 显示全部楼层
Mechanism of ETV6-RUNX1 Leukemiahe fusion of the . and . genes. Since its discovery in the 1990s, the function of the . fusion gene has attracted intense interest. In this chapter, we will summarize current knowledge on the clinical significance of ., the experimental models used to unravel its function in leukemogenesis, the iden
发表于 2025-3-25 20:17:31 | 显示全部楼层
发表于 2025-3-26 01:03:34 | 显示全部楼层
Molecular Basis and Targeted Inhibition of CBFβ-SMMHC Acute Myeloid Leukemiaand maintenance. The inv(16)(p13q22) rearrangement is a founding mutation and the associated CBFβ-SMMHC fusion protein is essential for the survival of inv(16) AML cells. This Chapter will discuss our understanding of the function of this fusion protein in disrupting hematopoietic homeostasis and cr
发表于 2025-3-26 06:14:38 | 显示全部楼层
发表于 2025-3-26 12:13:54 | 显示全部楼层
发表于 2025-3-26 12:45:08 | 显示全部楼层
Mechanism of ETV6-RUNX1 Leukemiatification of co-operating mutations and the mechanisms responsible for their acquisition, the function of the encoded transcription factor and finally, the future therapeutic approaches available to mitigate the associated disease.
发表于 2025-3-26 19:49:22 | 显示全部楼层
Roles of the , Enhancer in Normal Hematopoiesis and Leukemogenesisr of enhancers termed a super-enhancer. The . super-enhancer is observed in normal HSCs and T-cell acute lymphoblastic leukemia cells. In this review, we describe the discovery of eR1 and its roles in normal development and leukemogenesis, as well as its potential applications in stem cell research.
 关于派博传思  派博传思旗下网站  友情链接
派博传思介绍 公司地理位置 论文服务流程 影响因子官网 吾爱论文网 大讲堂 北京大学 Oxford Uni. Harvard Uni.
发展历史沿革 期刊点评 投稿经验总结 SCIENCEGARD IMPACTFACTOR 派博系数 清华大学 Yale Uni. Stanford Uni.
QQ|Archiver|手机版|小黑屋| 派博传思国际 ( 京公网安备110108008328) GMT+8, 2025-8-11 20:01
Copyright © 2001-2015 派博传思   京公网安备110108008328 版权所有 All rights reserved
快速回复 返回顶部 返回列表