Titlebook: RNP Particles, Splicing and Autoimmune Diseases; Johannes Schenkel Book 1998 Springer-Verlag Berlin Heidelberg 1998 Autoimmunkrankheit.RNA

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Isolation and Immunochemical Characterization of hnRNP Particles,ort from the nucleus to the cytoplasm is a multistep process: A modified nucleotide (cap structure) is added to the 5’ end of the primary transcript, intervening sequences (introns) are spliced and the 3’ ends are polyadenylated.

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Intrinsic Fluorescence Techniques for Studies on Protein-Protein and Protein-RNA Interactions in RNterial-consuming experiments, one would like to get as much information as possible from highly sensitive techniques. Analysis by light is particularly material conserving but this technique is quite often not used to its full potential. The purpose of this chapter is to show the potential of simple

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Methods in Immunolocalization of Autoantigens,o discriminate between foreign and self antigens. The mechanisms by which this discrimination is accomplished shall not be discussed here (there are numerous excellent textbooks on immunology available). However, in autoimmune disorders this discrimination fails to a certain extent due to mechanisms