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Titlebook: RNA and DNA Diagnostics; Volker A. Erdmann,Stefan Jurga,Jan Barciszewski Book 2015 Springer International Publishing Switzerland 2015 DNA

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Emergent Properties and Functions of Nanoconfined Nucleic Acid Architectures,pproach provides a powerful design tool for the development of nanoscale devices with transformative applications in multiple areas, including the detection of complex biomolecules, drug delivery, and in situ biomolecular synthesis. However, little is known of the effect of confinement on the functi
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Quadruplex Priming Amplification (QPA) for Nucleic Acid Diagnostics,ion due to (1) limited yield of product DNA (PCR plateau), (2) temperature cycling, and (3) complicated quantification methods. We have developed quadruplex priming amplification (QPA) to greatly simplify nucleic acid amplification and real-time quantification assays. The method relies on specifical
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Single-Molecule Strategies for DNA and RNA Diagnostics,ced an astonishing growth. In particular, during the last decade, the development of specific techniques to detect and analyse the structure and dynamics of nucleic acids at single-molecule level has revolutionised the field, and now it is possible to sequence a complete genome in record-breaking ti
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Electrochemical Biosensors for miRNA Detection,signing new methods for miRNA analysis includes sensitivity and multiplexing capability without PCR. In this chapter, novel electrochemical strategies for miRNA detection and quantification will be reviewed.
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