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Titlebook: RNA Metabolism in Trypanosomes; Albrecht Bindereif Book 2012 Springer-Verlag Berlin Heidelberg 2012 Gene Expression.Molecular Biology.RNA.

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rRNA Biogenesis in Trypanosomes,process involves the concerted action of the small nucleolar RNAs that direct cleavage at distinct sites in the intergenic spaces and modify the rRNA by 2′-.-methylation and pseudouridylation. The process also requires protein factors such as endonucleases, ATPases, GTPases, and helicases that media
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The RNA Interference Pathway in ,,eic acids, such as viruses or transcripts derived from retroposons and transposons. As a consequence cells go on red alert and activate specific defense mechanisms to eliminate the invaders. Among such mechanisms is the RNA interference (RNAi) pathway, which is triggered by long dsRNAs, destroys tar
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Translation in Trypanosomatids,somatids are well known for their unusual mechanisms and pathways, including .-splicing of primary mRNAs. The Spliced Leader RNA donates a unique, hypermethylated cap-4 structure to all mRNAs, which requires special adaptations by the cap-binding complex. The cap-binding eIF4F anchors the translatio
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Book 2012ness. Over the last few decades, research in trypanosome biology has revealed many unique and fascinating features, many of which have helped to establish new paradigms in other biological systems. This applies in particular to studies in gene expression and regulation, which benefit enormously from
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