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Titlebook: RNA Interference from Biology to Therapeutics; Kenneth A. Howard Book 2013 The Editor(s) (if applicable) and The Author(s), under exclusiv

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发表于 2025-3-21 16:50:36 | 显示全部楼层 |阅读模式
书目名称RNA Interference from Biology to Therapeutics
编辑Kenneth A. Howard
视频video
概述Addresses the role of different RNAi molecules in cellular processes as rational for diagnostic and therapeutic approaches.Covers RNAi therapeutic design to optimize siRNA potency and reduce off-targe
丛书名称Advances in Delivery Science and Technology
图书封面Titlebook: RNA Interference from Biology to Therapeutics; Kenneth A. Howard Book 2013 The Editor(s) (if applicable) and The Author(s), under exclusiv
描述The enormous potential of siRNA as a therapeutic has led to an explosion of interest from the scientific community. There has been intense interest from Big Pharma to capitalise on this new technology but the fact remains that delivery is a key determinant in realizing the full clinical potential of RNA interference. There is an urgent need for better delivery methods to take this technology forward. This book addresses the role of different RNAi molecules in cellular processes as rational for diagnostic and therapeutic approaches. This book will cover RNAi therapeutic design to optimize siRNA potency and reduce off-target effects and current delivery technologies to overcome both intracellular and extracellular barriers. The reader will gain an insight into RNA interference from the cellular mechanisms to screening to siRNA design right through to diagnostic and therapeutic applications.
出版日期Book 2013
关键词Gene Silencing; MicroRNA; Nanomedicine; Nanoparticles; RNA Interference (RNAi); RNAi Clinical Trials; RNAi
版次1
doihttps://doi.org/10.1007/978-1-4614-4744-3
isbn_softcover978-1-4899-9319-9
isbn_ebook978-1-4614-4744-3Series ISSN 2192-6204 Series E-ISSN 2192-6212
issn_series 2192-6204
copyrightThe Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Science+Busines
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Jesper B. Bramsen,Thomas B. Hansenstems for legal information provision. However, limited research has been conducted on the ‘demand side’ of legal information provision, though it is absolutely necessary to gain a good understanding of it, in order to design effective and useful systems for the provision of legal information; furth
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Morten Østergaard Andersen,Philipp Dillschneider,Jørgen Kjemsrimental and theoretical results available in the literatureThis book focuses on nanoscale electronic phase separation in a wide class of different materials, especially in strongly correlated electron systems. It features an extensive review of the field of inhomogeneous spin and charge states in c
创造性
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生命层
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行乞
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cleaver
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Michael Goldbergerial in this research field. Although precise studies on the structure and electronic properties of pentacene single crystals give us exact knowledge about this material, there exists a large gap between the fundamental physics of single crystal and device characteristics brought by practical polyc
amplitude
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发表于 2025-3-23 03:16:49 | 显示全部楼层
Frederico Pittella,Kazunori Kataokaerial in this research field. Although precise studies on the structure and electronic properties of pentacene single crystals give us exact knowledge about this material, there exists a large gap between the fundamental physics of single crystal and device characteristics brought by practical polyc
A精确的
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Samira Lakhal,Samir El Andaloussi,Aisling J. O’Loughlin,Jinghuan Li,Matthew M. J. Woodtoelectron yield spectroscopy, which have been developed forThe book covers a variety of studies of organic semiconductors, from fundamental electronic states to device applications, including theoretical studies. Furthermore, innovative experimental techniques, e.g., ultrahigh sensitivity photoelec
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