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Titlebook: RNA Interference and Cancer Therapy; Methods and Protocol Lekha Dinesh Kumar Book 2019 Springer Science+Business Media, LLC, part of Spring

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VEGFA Gene Silencing in CXCR4-Expressing Cells via siRNA Delivery by Means of Targeted Peptide CarrFA gene expression in A172 glioblastoma cells and in EA.hy 926 endothelial cells. Also, delivery of anti-VEGFA siRNA/peptide complexes led to significant inhibition of endothelial cell migration. Our results showed that L1 peptide carrier modified with CXCR4 ligand is a promising tool for targeted s
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64Cu-Labeled Aptamers for Tumor-Targeted Radionuclide Delivery, using positron emission tomography (PET). Closely following this protocol allows many aptamers to be successfully radiolabeled to accurately and quantitatively trace their distribution in vivo for a wide range of medical applications.
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