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Titlebook: RNA Bioinformatics; Ernesto Picardi Book 2021Latest edition Springer Science+Business Media, LLC, part of Springer Nature 2021 Computation

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发表于 2025-3-21 17:41:07 | 显示全部楼层 |阅读模式
书目名称RNA Bioinformatics
编辑Ernesto Picardi
视频video
概述Includes cutting-edge techniques.Provides step-by-step detail essential for reproducible results.Contains key implementation from the experts
丛书名称Methods in Molecular Biology
图书封面Titlebook: RNA Bioinformatics;  Ernesto Picardi Book 2021Latest edition Springer Science+Business Media, LLC, part of Springer Nature 2021 Computation
描述This detailed book aims to provide an overview of novel bioinformatics resources for exploring diverse aspects of RNA biology. This edition focuses on methods dealing with non-coding RNA (miRNAs, circRNAs or lncRNAs), RNA modifications (m6A or RNA editing), single cell RNA-seq and statistical models to handle count data from RNA-seq experiments. The book also includes chapters based on the classical RNA bioinformatics methods, such as those for deciphering secondary and tertiary RNA structures; however, they are revised to take into account deep sequencing data. Finally, chapters describing methods to analyze RNA sequencing data from emerging third generation sequencing technologies that could provide interesting insights into the transcriptional process and its regulation are also included. .Written for the highly successful .Methods in Molecular Biology. series, chapters include the kind of expert implementation advice that encourages quality results. Comprehensive and up-to-date, .RNA Bioinformatics, Second Edition. serves as an ideal guide for researchers digging ever-deeper into the depths of the study of RNAs..The chapter ‘RNA-Seq Data Analysis in Galaxy‘ is open access under
出版日期Book 2021Latest edition
关键词Computational biology; RNA biology; RNA-Seq data; Database resources; Non-coding RNAs; RNA modifications
版次2
doihttps://doi.org/10.1007/978-1-0716-1307-8
isbn_softcover978-1-0716-1309-2
isbn_ebook978-1-0716-1307-8Series ISSN 1064-3745 Series E-ISSN 1940-6029
issn_series 1064-3745
copyrightSpringer Science+Business Media, LLC, part of Springer Nature 2021
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Computational Analysis of circRNA Expression Data,ally reproducible analysis of circRNA expression starting for a public RNA-Seq experiment. The main steps of circRNA prediction, annotation, classification, sequence reconstruction, quantification, and differential expression are illustrated.
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Advanced Design of Structural RNAs Using RNARedPrint,erties. This chapter describes how to use the software . for the de novo rational design of RNA sequences adopting one or several desired secondary structures. Depending on the application, these structures could represent alternate configurations or kinetic pathways. The software makes such design
发表于 2025-3-22 16:32:19 | 显示全部楼层
Modeling and Predicting RNA Three-Dimensional Structures,cs-based approaches and molecular dynamics simulations are not tractable on large molecules with all-atom models. To address this issue, coarse-grained models of RNA three-dimensional structures have been developed. In this chapter, we describe a graphical modeling based on the Leontis–Westhof exten
发表于 2025-3-22 19:21:06 | 显示全部楼层
Motif Discovery from CLIP Experiments, RNA-Binding Proteins, and several methods have been developed to meet the need of fast and efficient discovery of interaction motifs. Recent advances have increased the amount of data produced by experimental assays and there is no available method suitable for the analysis of all type of results.
发表于 2025-3-22 23:07:32 | 显示全部楼层
Profiling of RNA Structure at Single-Nucleotide Resolution Using nextPARS, secondary structure of RNAs is central to understanding RNA function and evolution. RNA structure probing techniques coupled to high-throughput sequencing allow determining structural features of RNA molecules at transcriptome-wide scales. Our group recently developed a novel Illumina-based impleme
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Using RNentropy to Detect Significant Variation in Gene Expression Across Multiple RNA-Seq or Singlhave been proposed to model and detect differential gene expression based on the comparison of transcript abundances across different samples. However, state-of-the-art methods for this task are usually designed for pairwise comparisons, that is, can identify significant variation of expression only
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