Titlebook: RNA Binding Proteins; New Concepts in Gene Kathryn Sandberg (Associate Professor),Susan E. Mu Book 2002 Springer Science+Business Media New

天空

Translational Initiation of Ornithine Decarboxylase mRNAy fast turnover of ODC (half-life of minutes to an hour), the cellular level of ODC protein and thus the enzyme activity is rapidly altered when the synthesis and/or degradation of the enzyme is changed.

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antedate

RNA Binding by Members of the 70-kDa Family of Molecular Chaperonesan 70-kDa super-family of molecular chaperones (hsp70, hsc70, hsp110 and grp170), their inherent RATA binding properties. The monograph highlights the RATA sequence preference as well as the RNA-binding domain of these proteins. The influence of ATP and a peptide substrate on RNA-binding —all key co

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Post-Transcriptional Control of the GAP-43 mRNA by the ELAV-Like Protein HuDe activation of protein kinase C (PKC) and is mediated by the interaction of highly conserved sequences in the 3’ untranslated region (3 ‘UTR) of the mRNA with neuronal-specific RNA-binding proteins. One of these proteins was recently identified as the ELAV-like protein HuD. SLAV is an RNA-binding p

Expiration

RNA-Dependent Protein Kinasesfor studying RNA: protein interaction because its activity depends on binding to dsRNA but not DNA, single-stranded RNA, or RIVA:DNA hybrids. Well-known for mediating the antiviral effects of interferons (IFNs), PKR is also implicated in regulating cell differentiation, signal transduction, and in e

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Regulation of Messenger Rna-Binding Proteins by Protein Kinases A and Cjor signal transduction pathways that control gene expression involve activation of protein kinase A (PKA) (2) and protein kinase C (PKC) (3). Indeed, evidence has accumulated over recent years showing that the stability of a number of mRNA species is changed by extracellular signals that activate P

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Cytochrome P450 RNA—Protein Interactionsting with their mRNA in an inducer-dependent manner. The strategy used to characterize the RNA protein interaction and to identify the relevant RNA sequences as well as the regulatory factors are described in this chapter.

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Regulation of G-Protein Coupled Receptor Cytosolic mRNA Binding Proteinson the regulation of GPCRs via cytosolic RNA binding proteins that, through interaction with specific sequences or structures in the mRNA, contribute to determining the level of protein expression by altering the rate of mRNA translation or its stability. Highlighted are our studies on RNA binding p

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