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Titlebook: RNA Binding Proteins; New Concepts in Gene Kathryn Sandberg (Associate Professor),Susan E. Mu Book 2002 Springer Science+Business Media New

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发表于 2025-3-21 16:05:36 | 显示全部楼层 |阅读模式
书目名称RNA Binding Proteins
副标题New Concepts in Gene
编辑Kathryn Sandberg (Associate Professor),Susan E. Mu
视频video
丛书名称Endocrine Updates
图书封面Titlebook: RNA Binding Proteins; New Concepts in Gene Kathryn Sandberg (Associate Professor),Susan E. Mu Book 2002 Springer Science+Business Media New
描述RNA binding proteins are an exciting area of research in generegulation. A multitude of RNA-protein interactions are used toregulate gene expression including pre-mRNA splicing, polyadenylation,editing, transport, cytoplasmic targeting, translation and mRNAturnover. In addition to these post-transcriptional processes,RNA-protein interactions play a key role in transcription asillustrated by the life cycle of retroviruses. Unlike DNA, thestructure of RNA is highly variable and conformationally flexible,thus creating a number of unique binding sites and the potential forcomplex regulation by RNA binding proteins. .Although there is a wide range of topics included in this volume,general themes have been repeated, highlighting the overallintegrative nature of RNA binding proteins. The chapters have beenseparated into three different sections: Translational Control; mRNAMetabolism; and Hormonal and Homeostatic Regulation. The chapters ofthis volume were written with the seasoned investigator and student inmind. Summaries of key concepts are reviewed within each chapter aswell as guiding questions that can be used to stimulate classdiscussions. The Editors of this volume hope that this c
出版日期Book 2002
关键词DNA; G proteins; RNA; Translation; gene expression; genes; growth factor; insulin; insulin-like; metabolism; p
版次1
doihttps://doi.org/10.1007/978-1-4757-6446-8
isbn_softcover978-1-4419-4935-6
isbn_ebook978-1-4757-6446-8Series ISSN 1566-0729
issn_series 1566-0729
copyrightSpringer Science+Business Media New York 2002
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Poly-C Binding Proteins: Cellular Regulators of mRNA Fate and Functiontion. We will discuss possible mechanisms by which PCBPs may control different aspects of mRNA fate, including subcellular localization, regulation of translation, RNA stability as well as the role of PCBP in viral RNA replication.
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Post-Transcriptional Regulation of Iron Metabolismke and utilization of iron. The regulation of many iron metabolism proteins, including ferritin and transferrin receptor depends upon binding of iron regulatory proteins to RNA stem-loops found within the transcripts that encode these proteins.
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1566-0729 pression including pre-mRNA splicing, polyadenylation,editing, transport, cytoplasmic targeting, translation and mRNAturnover. In addition to these post-transcriptional processes,RNA-protein interactions play a key role in transcription asillustrated by the life cycle of retroviruses. Unlike DNA, th
发表于 2025-3-22 16:00:44 | 显示全部楼层
Site-Specific Cleavage of Insulin-Like Growth Factor II mRNAsvage of IGF-II mRNAs, which will be described in this chapter. The role of an RNA-binding protein that is associated with the highly structured RNA will be discussed as well as the requirements for recognition of the IGF-II mRNA by an endoribonuclease.
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The Role of RNA-Binding Proteins in IRES-Dependent Translationhinovirus (HRV) of Rhinovirus, encephalomyocarditis virus (EMCV) of Cardiovirus, hepatitis A virus (HA V) of Hepatovirus, and foot-and-mouth disease virus (FMDV) of Aphthovirus. It has been estimated that the incidence of human infections by picornaviruses exceeds 6 billion per year. Fortunately, th
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Translational Regulation of Masked Maternal mRNAs in Early Developmentiety of organisms. Overall, there is modest activation of the translational machinery at the time when the oocytes or eggs resume meiosis. More importantly, in every case examined in detail, specific sub-sets of mRNA are recruited onto polysomes from a masked form associated with proteins (mRNP). In
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Poly-C Binding Proteins: Cellular Regulators of mRNA Fate and Functiondentified. Recently, several laboratories showed that a family of proteins called poly(rC) binding proteins, PCBPs, play important roles in translation regulation and mRNA stabilization. PCBPs are RNA binding proteins that contain three copies of a conserved RNA binding domain called KH also found i
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