Titlebook: Rho Family GTPases; Ed. Manser (Principle Investigator) Book 2005 Springer Science+Business Media B.V. 2005 Regulation.cell biology.conser

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书目名称Rho Family GTPases影响因子(影响力)




书目名称Rho Family GTPases影响因子(影响力)学科排名




书目名称Rho Family GTPases网络公开度




书目名称Rho Family GTPases网络公开度学科排名




书目名称Rho Family GTPases被引频次




书目名称Rho Family GTPases被引频次学科排名




书目名称Rho Family GTPases年度引用




书目名称Rho Family GTPases年度引用学科排名




书目名称Rho Family GTPases读者反馈




书目名称Rho Family GTPases读者反馈学科排名

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Proteins and Cell Regulationhttp://image.papertrans.cn/r/image/820133.jpg

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https://doi.org/10.1007/1-4020-3462-8Regulation; cell biology; conservation; genecell; proteins; signal transduction; transcription; Proteomics

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The Rho GTPases,ytoskeleton, regulate cell polarity, microtubule dynamics, membrane transport pathways and modulate a variety of transcriptional events. Rho GTPases are biochemically and structually simple proteins: they cycle between two conformational states, with the GTP-bound form regarded as active, while the

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Structural Analysis of Rho Protein Complexes,actions. They include the classical switch regions in the nucleotide-binding site, and a unique switch region located on the opposite side of the protein. These switch regions communicate with each other and couple activation of Arfs by GTP to their recruitment to membranes. Variations in this cycle

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Activation of GTPases by Dock180 Family of Proteins,l GTPases. While conventional GEFs use a conserved DH-PH cassette for catalyzing GTP/GDP nucleotide exchange on Rho family GTPases, the Dock180 family members mediate nucleotide exchange via a novel evolutionarily conserved Docker/DHR2/CZH2 domain. The activation of distinct Rho-family GTPases by pa

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