书目名称 | Quasispecies: From Theory to Experimental Systems |
编辑 | Esteban Domingo,Peter Schuster |
视频video | |
概述 | Covers theoretical and experimental aspects of quasispecies.Includes the most recent developments in quasispecies research.Provides in-depth coverage of cutting-edge research in theory and experiment |
丛书名称 | Current Topics in Microbiology and Immunology |
图书封面 |  |
描述 | .This volume brings together recent developments in quasispecies theory extended to variable environments and practical applications in elucidating viral dynamics and treatment designs. In particular, the existence of an error threshold in rugged fitness landscapes has opened the way to a new antiviral strategy termed lethal mutagenesis, which is now under intensive theoretical, experimental and clinical investigation. As such the book explains how an understanding of quasispecies dynamics within infected organisms has increased our knowledge of viral disease events. From a clinical perspective, population dynamics highlights important problems for viral disease control, such as the selection of drug-resistant mutants that often accompanies treatment failures, and suggests means of increasing the effectiveness of antiviral treatments. The book is intended for students and scientists interested in basic and applied aspects of biophysics, chemistry, biology, evolution and medical virology. . |
出版日期 | Book 2016 |
关键词 | RNA interactions; Antiviral strategies; Lethal mutagenesis; Viral population dynamics; Virus spread; Vira |
版次 | 1 |
doi | https://doi.org/10.1007/978-3-319-23898-2 |
isbn_softcover | 978-3-319-79548-5 |
isbn_ebook | 978-3-319-23898-2Series ISSN 0070-217X Series E-ISSN 2196-9965 |
issn_series | 0070-217X |
copyright | The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Switzerl |