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Titlebook: Quantitative Structure-Activity Relationships; Proceedings of the C Miloň Tichý Conference proceedings 1976 Springer Basel AG 1976 Biologie

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楼主: 可怜
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The Influence of Lipophilicity on the Antibacterial Activity of Rifamycinshese drugs can be obtained for three steps of activity, namely enzyme systems, microorganisms and superior organisms; in this way a deeper understanding of their activity can be achieved by studying separately the factors affecting the intrinsic activity and the transport of the drug to the receptor
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Use of Structure-Activity Relationships to Estimate Toxicity of Inorganic Cationsorrelations between biological activities and values of various chemical or physico-chemical parameters of many organic compounds differing from each other by different substituents in the basic skeleton of the molecule were found. If the molecule of a substance is considered as it enters the organi
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Correlation Between Physico-Chemical Properties of Chemical Compounds and Indices of their Toxic Actand biological, in particular toxic, action on the other is more than one hundred years old. Prominent scientists of the last and the present centuries took part in the development of this field of science and now considerable experimental material and some theoretical conceptions are available.
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The Influence of Lipophilicity on the Antibacterial Activity of Rifamycins site. Among the various methods proposed for the quantitative approach to SAR we have chosen the well known method of Hansch, and we have used the .. values to express lipophilicity. The experimental work has been performed by thin-layer partition chromatography between silicon oil and water containing various proportions of acetone [1].
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On the Parabolic Relationship Between Biological Activity and Hydrophobicity of Drugs: Transport or aper is to discuss some criteria which may be helpful to discriminate between these two possibilities and, furthermore, to show that hydrophobic interactions probably dominate over transport in much more cases than is generally believed at present.
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