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Titlebook: Quantitative Physiology; Systems Approach Shangbin Chen,Alexey Zaikin Book 2020 Huazhong University of Science and Technology Press 2020 Qu

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发表于 2025-3-21 17:20:16 | 显示全部楼层 |阅读模式
书目名称Quantitative Physiology
副标题Systems Approach
编辑Shangbin Chen,Alexey Zaikin
视频video
概述Provides researchers with the modeling and computational studies of physiology.Covers basic methodology, case practices and advanced applications.Sets a paradigm for quantitative physiology by integra
图书封面Titlebook: Quantitative Physiology; Systems Approach Shangbin Chen,Alexey Zaikin Book 2020 Huazhong University of Science and Technology Press 2020 Qu
描述.Stephen Hawking says that the 21st century will be the century of complexity and indeed now systems biology or medicine means dealing with complexity. Both the genome and physiome have emerged in studying complex physiological systems. Computational and mathematical modeling has been regarded as an efficient tool to boost the understanding about living systems in normal or pathophysiological states..Covering applied methodology, basic case studies and complex applications, this volume provides researchers with an overview of modeling and computational studies of physiology (i.e. quantitative physiology), which is becoming an increasingly important branch of systems biology..This book aims to build multi-scale models to investigate functions in living systems and explain how biomolecules, cells, organs, organ systems and organisms carry out the chemical or physical functions. Some of the models addressed are related to gene expression, calcium signalling, neural activity,blood dynamics and bone mechanics..Combining theory and practice, with extensive use of MATLAB, this book is designed to establish a paradigm for quantitative physiology by integrating biology, mathematics, physics
出版日期Book 2020
关键词Quantitative Physiology; Multiscale Modeling; Genome; Physiome; Living System; Systems Biology
版次1
doihttps://doi.org/10.1007/978-981-33-4033-6
isbn_softcover978-981-33-4035-0
isbn_ebook978-981-33-4033-6
copyrightHuazhong University of Science and Technology Press 2020
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Modelling Neural Activity as pacemakers. How can we explain these different regimes with mathematical models? We start with more complicated Hodgkin-Huxley model of neuron firing, then simplify it to the FitzHugh-Nagumo model and analyse carefully its behaviour using the methodology of the phase space.
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Bone and Body Mechanicsematical modelling to explain its shortening under the load, or some features of its structure. Moreover, the bones demonstrate viscoelastic properties, and this is a very interesting challenge for a modeller to develop the simplest model of viscoelastic behaviour.
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Modelling Complex Phenomena in Physiologycomprehensive review on its modelling is presented. The kidney regulation is also mentioned and shown with the computational model. Furthermore, the heart physiome and brain projects are outlined. The integrated information is introduced with the most recent publication.
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978-981-33-4035-0Huazhong University of Science and Technology Press 2020
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https://doi.org/10.1007/978-981-33-4033-6Quantitative Physiology; Multiscale Modeling; Genome; Physiome; Living System; Systems Biology
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