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Titlebook: Quantitative Assessment in Epilepsy Care; Harry Meinardi,Joyce A. Cramer,Antonio Martins Sil Book 1993 Springer Science+Business Media New

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书目名称Quantitative Assessment in Epilepsy Care
编辑Harry Meinardi,Joyce A. Cramer,Antonio Martins Sil
视频video
丛书名称NATO Science Series A:
图书封面Titlebook: Quantitative Assessment in Epilepsy Care;  Harry Meinardi,Joyce A. Cramer,Antonio Martins Sil Book 1993 Springer Science+Business Media New
描述Advances in epilepsy in recent decades have allowed for improved algorithms for diagnosis and a common understanding of terminology with the development of the International Classifications of Seizures and the Epilepsies. Nevertheless, no common system exists for the estimation of epilepsy severity or its impact on quality of life. Therefore, epileptologists lack the ability to make quantitative assessments of individual patients for comparison of care or for meta-analyses in clinical trials. This book on the Quantitative Assessment of Epilepsy Care approaches this omission by addressing the potential application of clinimetrics within the framework of epilepsy treatment. Clinimetrics is a fast growing discipline concerned with the quantification of clinical symptoms with respect to decision making relating to diagnosis, treatment, and prognosis. These methods allow for the development and validation of clinical scoring systems. For example, the Glasgow Coma Scale is widely used. As a chronic disorder, epilepsy would benefit from clinimetric methodology to create uniformity and to allow for comparisons among evaluations. In addition, epileptologists have not yet developed assessmen
出版日期Book 1993
关键词assessment; care; classification; clinical trial; development; diagnosis; drug; epilepsy; methodology; patien
版次1
doihttps://doi.org/10.1007/978-1-4615-2990-3
isbn_softcover978-1-4613-6302-6
isbn_ebook978-1-4615-2990-3
copyrightSpringer Science+Business Media New York 1993
The information of publication is updating

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Statistical Aspects of the Measurement of Clinical Care in Epilepsy,cterised by sudden, brief attacks of altered consciousness, motor activity, or sensory phenomena” (Taber 1985). The definition though terse encapsulates the essential features of epilepsy and hints at the heterogeneity of the disorder especially with the “catch-all” term “sensory phenomena.” From th
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Seizure Frequency as Treatment Effect Parameter,sometimes inextricable (.); and seizure factors (.)have different degrees of importance on patient status (neurological, psychiatric or psychological well—being) influencing epilepsy evolution. These variables are important not only for epilepsy prognosis but they also tend to operate whatever the s
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Seizure Frequency as Treatment Effect Parameter in Epileptic Patients: A Critical Appraisal of the inst Epilepsy (.) “Seizure frequency” is one of the evaluation parameters from late phase I studies onwards. In phase II studies other seizure related parameters are added such as length of seizure-free intervals, seizure duration and seizure pattern.
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Quantitative Approaches to Seizure Severity,mber of seizures. However, subjective and qualitative aspects of seizures are difficult to quantify. The major problems inherent in assessing seizure severity include dependence on patient recall and reporting, as well as observer documentation. Reports focus on whether the patient was alert and in
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Quantitative Assessment of Adverse Drug Effects,seizure control is effective at modest drug dose (., ., .). However, those patients whose seizure control cannot be realized by any single or combination of drugs often need to have their dose increased to a point of maximal tolerance as evidenced by undesirable adverse effects. In fact, while the c
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