| 书目名称 | Quantitative Analysis of Cellular Drug Transport, Disposition, and Delivery | | 编辑 | Gus R. Rosania,Greg M. Thurber | | 视频video | | | 概述 | Includes cutting-edge techniques.Provides step-by-step detail essential for reproducible results.Features information that applies to a wide array of research areas | | 丛书名称 | Methods in Pharmacology and Toxicology | | 图书封面 |  | | 描述 | This thorough book explores some of the most important methods and concepts affecting the quantitative analysis of the transport, targeting, and disposition of chemicals within cells, which in turn impact the macroscopic pharmacokinetics of chemical agents in the whole organism. The first half of the volume focuses on small organic molecules with drug-like characteristics, while the second half delves into the cellular pharmacokinetics of biologics and other macromolecules, including peptide therapeutics, cyclotides, antibodies, as well as nanoparticles, thus creating a comprehensive treatise that approaches cellular pharmacokinetics from the different perspectives of pharmaceutical scientists, chemical biologists, medicinal chemists, and protein engineers dealing with very different chemical agents spanning a wide range of sizes, physicochemical properties, and targeting mechanisms. Written for the .Methods in Pharmacology and Toxicology. series, chapters provide the kind of key detail and expert implementation advice that leads to excellent results in the lab. Synthetic biologists, biophysicists, and bioengineers are amongst the long list of scientists who could benefit from read | | 出版日期 | Book 2021 | | 关键词 | Pharmacokinetics; Drug development; Small molecule pharmacology; Biologics; Macromolecule transport; Nano | | 版次 | 1 | | doi | https://doi.org/10.1007/978-1-0716-1250-7 | | isbn_softcover | 978-1-0716-1252-1 | | isbn_ebook | 978-1-0716-1250-7Series ISSN 1557-2153 Series E-ISSN 1940-6053 | | issn_series | 1557-2153 | | copyright | Springer Science+Business Media, LLC, part of Springer Nature 2021 |
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发表于 2025-3-21 18:46:19
