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Titlebook: Psychoneuroimmunology; Methods and Protocol Qing Yan Book 2025Latest edition The Editor(s) (if applicable) and The Author(s), under exclusi

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The MRL Model: A Valuable Tool in Studies of Autoimmunity-Brain Interactionsuffering from lupus and other autoimmune disorders. This review highlights the importance of the MRL model as a useful preparation for understanding the links between the immune system and brain function.
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Psychoneuroimmunology of Mood Disordersemphasizing their association with autoimmunity/inflammatory conditions, chronic low-grade systemic inflammation, T cell overactivation, and immunosenescence. This perspective underscores the notion that MDD and BD are not solely brain disorders, highlighting their nature as multi-system conditions.
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Purpose in Life and Stress Reactivitye to health, namely stress reactivity. Across survey, experimental, and daily diary studies, research demonstrates that sense of purpose may yield a homeostatic function, insofar that it helps individuals stay the course to progress toward their purpose in life. Future research is needed to examine
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Personality and Psychoneuroimmunology: A Systems Biology Perspectiveith specific traits linked to stress influencing neural behavior and psychophysiological disorders. Gene expression networks associated with personality affect neuronal plasticity, epigenetic processes, and adaptive behaviors, highlighting the importance of systems biology mechanisms. Systemic infla
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Psychoneuroimmunology of Mood Disorders, and inflammation. This chapter explores the complex interplay involving immune and metabolic dysfunction in the pathophysiology of these disorders, emphasizing their association with autoimmunity/inflammatory conditions, chronic low-grade systemic inflammation, T cell overactivation, and immunosen
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Biomarkers Unveiling the Interplay of Mind, Nervous System, and Immunity between the immune and central nervous systems (CNS). There is a preponderance of evidence supporting the fact that immunological pathways and neuroinflammation are involved in the pathophysiology of multiple neurological and mental health conditions. In this chapter, we have explored various neuro
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