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Titlebook: p53 in the Clinics; Pierre Hainaut,Magali Olivier,Klas G. Wiman Book 2013 Springer Science+Business Media New York 2013 TP53.cancer resear

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书目名称p53 in the Clinics
编辑Pierre Hainaut,Magali Olivier,Klas G. Wiman
视频video
概述Focuses on recent advances in translational research on p53.Explores the significance of the genetic diversity of p53.Discusses mutations as biomarkers in molecular pathology
图书封面Titlebook: p53 in the Clinics;  Pierre Hainaut,Magali Olivier,Klas G. Wiman Book 2013 Springer Science+Business Media New York 2013 TP53.cancer resear
描述This project follows on the success of the book "25 years of p53", published by Springer in 2006. Since this publication, there have been considerable advances on the potential application of p53 into the clinics. The goal of this book is to capture these developments and to appeal to a clinical and medical audience beyond the one which was the primary target of "25 years of p53".
出版日期Book 2013
关键词TP53; cancer research; chromosome 17; protein kinase; tumor suppressor protein; ubiquitin ligases
版次1
doihttps://doi.org/10.1007/978-1-4614-3676-8
isbn_softcover978-1-4899-9217-8
isbn_ebook978-1-4614-3676-8
copyrightSpringer Science+Business Media New York 2013
The information of publication is updating

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Assessing , Status in Human Tumors: Lessons from Breast Cancer,on detection methods, and be more applicable in different aspects of clinical decision making. As breast cancer is one of the cancer diseases where . mutation status shows the most significant prognostic impact and clinical potential, the chapter is based on experiences from research on this tumor type.
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The p53 Family and Stem Cell Biology,se features are achieved by a fine-tuned control of proliferation and maintenance of the undifferentiated condition. Transcription factors such as Nanog, Sox, and Oct-4 and extrinsic factors (LIF, BMP, and FGF) have been demonstrated to play a critical role in the regulation of stemness. Because ste
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