书目名称 | Proteomic and Ionomic Study for Identification of Biomarkers in Biological Fluid Samples of Patients with Psychiatric Disorders and Healthy Individuals |
编辑 | Jemmyson Romário de Jesus |
视频video | http://file.papertrans.cn/762/761866/761866.mp4 |
概述 | Nominated as an outstanding Ph.D. thesis by the University of Campinas, Brazil.Helps readers understand the proteome and metallome of patients with bipolar disorder.Provides simple and rapid sample pr |
丛书名称 | Springer Theses |
图书封面 |  |
描述 | This book presents an exploratory analysis based on proteomic and ionomics studies comparing the blood serum of patients with bipolar disorder (BD), healthy controls, patients with schizophrenia (SCZ), and patients with other disorders (OD) in order to identify biomarkers of BD. Bipolar disorder is a psychiatric condition that affects thousands of people worldwide. The absence of biomarkers for BD has resulted in misdiagnosis and ineffective treatment in some patients, causing additional health problems and high costs for health systems. As such, this book evaluates various strategies for sample preparation for proteomic and ionomic studies in order to simplify complex serum samples and allow the quantification of chemical species (proteins and metal ions), which are potential candidates for BD biomarkers. In addition, it describes the development of a new membrane-based methodology for extracting urine proteins to be used in biomarker discovery. |
出版日期 | Book 2019 |
关键词 | Depletion of Abundant Proteins; Proteomic Profiling; Immunoaffinity Techniques; Metallomics; Magnetic Na |
版次 | 1 |
doi | https://doi.org/10.1007/978-3-030-29473-1 |
isbn_softcover | 978-3-030-29475-5 |
isbn_ebook | 978-3-030-29473-1Series ISSN 2190-5053 Series E-ISSN 2190-5061 |
issn_series | 2190-5053 |
copyright | Springer Nature Switzerland AG 2019 |